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Other Balance Sheet Accounts (Tables)
12 Months Ended
Dec. 31, 2012
Other Balance Sheet Accounts [Abstract]  
Summary of property and equipment
                 
    2012     2011  

Equipment

  $ 19,660     $ 19,147  

Leasehold improvements

    7,992       7,992  
   

 

 

   

 

 

 
      27,652       27,139  

Less accumulated depreciation and amortization

    (22,368     (20,913
   

 

 

   

 

 

 
    $ 5,284     $ 6,226  
   

 

 

   

 

 

 
Summary of Intangible assets
                 
    2012     2011  

Licensed technology rights

  $ 4,015     $ 4,015  

Patent application costs

    6,420       6,093  
   

 

 

   

 

 

 
      10,435       10,108  

Accumulated amortization licensed technology rights

    (3,931     (3,906

Accumulated amortization patent costs

    (3,691     (3,331
   

 

 

   

 

 

 
    $ 2,813     $ 2,871  
   

 

 

   

 

 

 
Summary of accounts payable and accrued expenses
                 
    2012     2011  

Employee compensation

  $ 3,858     $ 3,653  

Clinical trial accruals

    660       1,681  

Accounts payable

    377       351  

Deferred rent

    307       247  

Other accrued liabilities

    427       430  
   

 

 

   

 

 

 
    $ 5,629     $ 6,362