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Collaborative Arrangement, Rights and Obligations, Maximum Aggregate Milestone Payments

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Collaborative Arrangement, Rights and Obligations, One-Time Cash Payment

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Collaborative Arrangement, Rights and Obligations, Royalty Payments, Percent of Net Sales

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Milestone Payment

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Payments for Additional Product Approval

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Payments For Submission of Apllication

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Research and Development Expense, Future Payment, Payment One

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Research and Development Expense, Future Payment, Payment Two

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Revenue, Remaining Performance Obligation, Variable Consideration, Royalty Percentage

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Stock Issued During Period, Shares, License Agreement

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Stock Issued During Period, Value, License Agreement

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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The amount of cash paid for royalties during the current period.

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The cash outflow to acquire asset without physical form usually arising from contractual or other legal rights, excluding goodwill.

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The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use.

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Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

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STRATEGIC AGREEMENTS (Details)			3 Months Ended
STRATEGIC AGREEMENTS (Details)	May 03, 2022	Aug. 27, 2021 USD ($) shares	Mar. 31, 2022 USD ($)	Mar. 31, 2021 USD ($)	Feb. 02, 2022 USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Research and development expense, future payment, payment two		$ 107,500,000
Milestone payment		1,000,000.0
Research and development			$ 6,013,000	$ 6,052,000
Revenue			92,000	17,000
Royalty revenue \| Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue			92,000	17,000
Carna Biosciences, Inc.
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaborative arrangement, rights and obligations, one-time cash payment					$ 2,000,000.0
Collaborative arrangement, rights and obligations, maximum aggregate milestone payments					$ 258,000,000.0
Collaborative arrangement, rights and obligations, royalty payments, percent of net sales					0.10
Voronoi Inc.
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Payments to acquire intangible assets		2,500,000
Issuance of common stock under license agreement		$ 2,000,000.0
Issuance of common stock under license agreement (in shares) \| shares		2,816,901
Research and development expense, future payment, payment one		$ 211,000,000.0
Bodor Laboratories, Inc.
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Payments For Submission of Apllication			300,000
Cash payment			500,000
Payments for additional product approval			100,000
Value of shares issued in agreement			1,000,000
Research and development			$ 0	$ 0
Bodor Laboratories, Inc. \| Minimum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Royalty percentage			50.00%
Bodor Laboratories, Inc. \| Maximum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Royalty percentage			55.00%
Botanix \| Subsequent Event
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaborative agreement, percentage of actual fees to be paid	18.00%