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Certain Transactions - Other Transactions - Additional Information (Detail) - USD ($)
$ in Millions
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Jan. 08, 2018
May 12, 2017
Oct. 31, 2021
Aug. 31, 2021
Sep. 30, 2016
Sep. 30, 2021
Sep. 30, 2020
Mar. 31, 2020
Sep. 30, 2016
Sep. 30, 2021
Dec. 31, 2018
Dec. 31, 2017
Alder [Member]                        
Noncash or Part Noncash Acquisitions [Line Items]                        
Upfront payment $ 25                      
Milestone payment               $ 25        
Collaborative agreement milestone payments $ 150                      
Otsuka [Member]                        
Noncash or Part Noncash Acquisitions [Line Items]                        
Upfront payment   $ 50                    
Milestone payment           $ 35 $ 15          
Celltrion [Member]                        
Noncash or Part Noncash Acquisitions [Line Items]                        
Refundable payment           60       $ 60    
Total associated cost           $ 160       160    
Regeneron [Member]                        
Noncash or Part Noncash Acquisitions [Line Items]                        
Upfront payment                 $ 250      
Collaborative agreement milestone payments         $ 2,230           $ 120 $ 120
Research and development costs         $ 1,000              
Alvotech [Member]                        
Noncash or Part Noncash Acquisitions [Line Items]                        
Collaborative agreement milestone payments                   $ 450    
MedinCell [Member]                        
Noncash or Part Noncash Acquisitions [Line Items]                        
Collaborative agreement milestone payments       $ 112                
MODAG [Member] | Subsequent Event [Member]                        
Noncash or Part Noncash Acquisitions [Line Items]                        
License agreement potential aggregate milestone payments amount     $ 80