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Revenue Recognition - Schedule of Disaggregated Net Product Sales (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Product Information [Line Items]      
Net product sales $ 86,346 $ 88,638 $ 145,968
CINVANTI      
Product Information [Line Items]      
Net product sales 73,507 87,815 132,162
SUSTOL      
Product Information [Line Items]      
Net product sales 9,915 $ 823 $ 13,806
ZYNRELEF      
Product Information [Line Items]      
Net product sales $ 2,924