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Business - Additional Information (Details)
$ in Millions
3 Months Ended
Mar. 31, 2021
USD ($)
Jan. 01, 2021
Country
Business [Line Items]    
Cash, cash equivalents and short-term investments | $ $ 166.5  
HTX-034 | Europe    
Business [Line Items]    
Number of countries approved the drug | Country   31
HTX-034    
Business [Line Items]    
Percentage of patients remained opioid free 45.50%  
Percentage of reduction in pain intensity 71.00%