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Note 7 - Realignment of Goals and Objectives and New Development Focus (Details Textual) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2018
Dec. 31, 2018
Restructuring and Related Cost, Expected Cost, Total   $ 9.4
Restructuring Plan [Member] | General and Administrative Expense [Member]    
Restructuring Charges, Total $ 0.5  
Restructuring Plan [Member] | Employee Severance [Member]    
Restructuring and Related Cost, Expected Cost, Total   5.5
Restructuring Plan [Member] | Accelerated Non-Cash Stock Option Expense [Member]    
Restructuring and Related Cost, Expected Cost, Total   $ 3.9