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Note 8 - Stockholders' Equity - Valuation Assumptions (Details)
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Employee Stock Option [Member]      
Risk-free interest rate 2.10% 1.70% 1.70%
Dividend yield
Volatility 74.00% 89.10% 92.70%
Expected life (years) (Year) 6 years 6 years 6 years
Employee Stock Purchase Plan [Member]      
Risk-free interest rate 1.20% 0.40% 0.10%
Dividend yield
Volatility 50.00% 68.30% 86.70%
Expected life (years) (Year) 180 days 180 days 180 days