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Note 6 - Stockholders' Equity (Details Textual) - USD ($)
1 Months Ended 6 Months Ended
Jun. 30, 2015
Jun. 30, 2016
Jun. 30, 2015
Jun. 30, 2011
Common Stock [Member] | Private Placement 2011 [Member]        
Stock Issued During Period, Shares, New Issues   2,395,700 209,607  
Share-based Compensation Arrangement by Share-based Payment Award, Non-Option Equity Instruments, Exercised   2,965,477 260,480  
Proceeds from Warrant Exercises   $ 0 $ 0  
Common Stock [Member]        
Stock Issued During Period, Shares, New Issues 5,520,000      
Sale of Stock, Price Per Share $ 24.75   $ 24.75  
Proceeds from Issuance or Sale of Equity $ 128,199,000      
Payments of Stock Issuance Costs $ 8,421,000      
Private Placement 2011 [Member]        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights       4,000,000
Class of Warrant or Right, Exercise Price of Warrants or Rights       $ 3.60
Proceeds from Issuance or Sale of Equity   $ 128,205,000  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Net   530,840 713,381  
Proceeds from Stock Options Exercised   $ 4,755,000 $ 6,306,000  
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized   $ 65,205,000    
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition   2 years 73 days