Inventory - Additional Information (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022	Dec. 31, 2022
Inventory [Line Items]
Total inventory	$ 44,623		$ 44,623		$ 54,573
ZYNRELEF
Inventory [Line Items]
Total inventory	19,900		19,900		30,900
Cost of product sales, charges	7,500	$ 2,500	12,800	$ 2,500
CINVANTI
Inventory [Line Items]
Total inventory	21,400		21,400		19,900
SUSTOL
Inventory [Line Items]
Total inventory	2,300		2,300		2,600
APONVIE
Inventory [Line Items]
Total inventory	$ 1,000		$ 1,000		$ 1,200