-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 ARu8Vkd9xMKmjBlUWIOwGTVf4Fyk6FMtVhi7cLk9c4GgIrUrcY1Ve5A6Ul0F6ZBz
 5m3jFz+2y92FkneKrTz81Q==

<SEC-DOCUMENT>0000898432-03-000633.txt : 20030724
<SEC-HEADER>0000898432-03-000633.hdr.sgml : 20030724
<ACCEPTANCE-DATETIME>20030711193935
ACCESSION NUMBER:		0000898432-03-000633
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20030707
FILED AS OF DATE:		20030714

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			KIMBERLIN KEVIN
		CENTRAL INDEX KEY:			0000904841

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-31732
		FILM NUMBER:		03784459

	BUSINESS ADDRESS:	
		STREET 1:		SPENCER TRASK SECURITIES INC
		STREET 2:		535 MADISON AVENUE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		2123555565

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			IMMUNE RESPONSE CORP
		CENTRAL INDEX KEY:			0000817785
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				330255679
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		5935 DARWIN COURT
		CITY:			CARLSBAD
		STATE:			CA
		ZIP:			92008
		BUSINESS PHONE:		6194317080

	MAIL ADDRESS:	
		STREET 1:		5935 DARWIN COURT
		CITY:			CARLSBAD
		STATE:			CA
		ZIP:			92008
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>kevinbkimberlin-form4_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<!-- - EDGAR Ease Plus 1.0                                   04/22/03  TZ    -->
<ownershipDocument>
    <schemaVersion>X0101</schemaVersion>

    <documentType>4</documentType>
   <periodOfReport>2003-07-07</periodOfReport>
    <issuer>
        <issuerCik>0000817785</issuerCik>
        <issuerName>IMMUNE RESPONSE CORP</issuerName>
        <issuerTradingSymbol>IMNR</issuerTradingSymbol>
   </issuer>
   <reportingOwner>
      <reportingOwnerId>
            <rptOwnerCik>0000904841</rptOwnerCik>
            <rptOwnerName>KIMBERLIN KEVIN</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>  </rptOwnerStreet1>
            <rptOwnerStreet2>  </rptOwnerStreet2>
            <rptOwnerCity>  </rptOwnerCity>
            <rptOwnerState>  </rptOwnerState>
            <rptOwnerZipCode>  </rptOwnerZipCode>
        </reportingOwnerAddress>
            <reportingOwnerRelationship>
         <isDirector>1</isDirector>
         <isOfficer>0</isOfficer>
         <isTenPercentOwner>1</isTenPercentOwner>
         <isOther>0</isOther>
       </reportingOwnerRelationship>
   </reportingOwner>
   <nonDerivativeSecurity>
      <securityTitle>
         <value>Common Stock, par value $.0025 per share</value>
      </securityTitle>
      <transactionDate>
         <value>2003-07-07</value>
      </transactionDate>
      <transactionCoding>
         <transactionFormType>4</transactionFormType>
         <transactionCode>P</transactionCode>
         <equitySwapInvolved>0</equitySwapInvolved>
      </transactionCoding>
      <transactionAmounts>
         <transactionShares>
           <value>2662332</value>
         </transactionShares>
         <transactionValue>
           <value>1.33</value>
         </transactionValue>
         <transactionAcquiredDisposedCode>
           <value>A</value>
         </transactionAcquiredDisposedCode>
      </transactionAmounts>
     <postTransactionAmounts>
         <sharesOwnedFollowingTransaction>
           <value>9483139</value>
            <footnoteId id="F1"/>
         </sharesOwnedFollowingTransaction>
      </postTransactionAmounts>
      <ownershipNature>
         <directOrIndirectOwnership>
            <value>I</value>
         </directOrIndirectOwnership>
         <natureOfOwnership>
            <value>See Notes</value>
            <footnoteId id="F2"/>
            <footnoteId id="F3"/>
            <footnoteId id="F4"/>
         </natureOfOwnership>
      </ownershipNature>
   </nonDerivativeSecurity>
   <derivativeSecurity>
      <securityTitle>
         <value>Class A warrants</value>
      </securityTitle>
      <conversionOrExercisePrice>
         <value>1.33</value>
      </conversionOrExercisePrice>
      <transactionDate>
         <value>2003-07-07</value>
      </transactionDate>
      <transactionCoding>
         <transactionFormType>4</transactionFormType>
         <transactionCode>X</transactionCode>
         <equitySwapInvolved>0</equitySwapInvolved>
      </transactionCoding>
      <transactionAmounts>
         <transactionShares>
           <value>1774888</value>
            <footnoteId id="F5"/>
            <footnoteId id="F6"/>
         </transactionShares>
         <transactionValue>
           <value>2360601</value>
         </transactionValue>
         <transactionAcquiredDisposedCode>
           <value>A</value>
         </transactionAcquiredDisposedCode>
      </transactionAmounts>
      <exerciseDate>
         <value>2002-12-10</value>
      </exerciseDate>
      <expirationDate>
         <value>2003-07-07</value>
      </expirationDate>
      <underlyingSecurity>
         <underlyingSecurityTitle>
           <value>Common Stock Class B Warrants</value>
         </underlyingSecurityTitle>
         <underlyingSecurityShares>
           <value>1774888</value>
            <footnoteId id="F5"/>
            <footnoteId id="F6"/>
         </underlyingSecurityShares>
      </underlyingSecurity>
      <postTransactionAmounts>
         <sharesOwnedFollowingTransaction>
           <value>24606788</value>
            <footnoteId id="F7"/>
            <footnoteId id="F8"/>
         </sharesOwnedFollowingTransaction>
      </postTransactionAmounts>
      <ownershipNature>
         <directOrIndirectOwnership>
           <value>I</value>
         </directOrIndirectOwnership>
         <natureOfOwnership>
           <value>See Notes</value>
            <footnoteId id="F5"/>
            <footnoteId id="F6"/>
         </natureOfOwnership>
      </ownershipNature>
   </derivativeSecurity>
   <derivativeSecurity>
      <securityTitle>
         <value>8% Convertible Debenture due 2005</value>
      </securityTitle>
      <conversionOrExercisePrice>
         <value>1.4570</value>
      </conversionOrExercisePrice>
      <transactionDate>
         <value>2003-07-07</value>
      </transactionDate>
      <transactionCoding>
         <transactionFormType>4</transactionFormType>
         <transactionCode>H</transactionCode>
         <equitySwapInvolved>0</equitySwapInvolved>
      </transactionCoding>
      <transactionAmounts>
         <transactionShares>
           <value>2611709</value>
            <footnoteId id="F5"/>
            <footnoteId id="F6"/>
         </transactionShares>
         <transactionValue>
           <value>3805260.27</value>
            <footnoteId id="F5"/>
            <footnoteId id="F6"/>
         </transactionValue>
         <transactionAcquiredDisposedCode>
           <value>D</value>
         </transactionAcquiredDisposedCode>
      </transactionAmounts>
      <exerciseDate>
         <value>2003-06-10</value>
      </exerciseDate>
      <expirationDate>
         <value>2003-07-07</value>
      </expirationDate>
      <underlyingSecurity>
         <underlyingSecurityTitle>
           <value>Common Stock</value>
         </underlyingSecurityTitle>
         <underlyingSecurityShares>
           <value>2611709</value>
         </underlyingSecurityShares>
      </underlyingSecurity>
      <postTransactionAmounts>
         <sharesOwnedFollowingTransaction>
           <value>21995079</value>
            <footnoteId id="F7"/>
            <footnoteId id="F8"/>
         </sharesOwnedFollowingTransaction>
      </postTransactionAmounts>
      <ownershipNature>
         <directOrIndirectOwnership>
           <value>I</value>
         </directOrIndirectOwnership>
         <natureOfOwnership>
           <value>See Notes</value>
            <footnoteId id="F5"/>
            <footnoteId id="F6"/>
         </natureOfOwnership>
      </ownershipNature>
   </derivativeSecurity>
   <derivativeSecurity>
      <securityTitle>
         <value>8% Convertible Debenture due 2005</value>
      </securityTitle>
      <conversionOrExercisePrice>
         <value>1.4570</value>
      </conversionOrExercisePrice>
      <transactionDate>
         <value>2003-07-07</value>
      </transactionDate>
      <transactionCoding>
         <transactionFormType>4</transactionFormType>
         <transactionCode>H</transactionCode>
         <equitySwapInvolved>0</equitySwapInvolved>
      </transactionCoding>
      <transactionAmounts>
         <transactionShares>
           <value>1006986</value>
            <footnoteId id="F5"/>
            <footnoteId id="F6"/>
         </transactionShares>
         <transactionValue>
           <value>1467178.03</value>
            <footnoteId id="F5"/>
            <footnoteId id="F6"/>
         </transactionValue>
         <transactionAcquiredDisposedCode>
           <value>A</value>
         </transactionAcquiredDisposedCode>
      </transactionAmounts>
      <exerciseDate>
         <value>2003-07-07</value>
      </exerciseDate>
      <expirationDate>
         <value>2006-07-07</value>
      </expirationDate>
      <underlyingSecurity>
         <underlyingSecurityTitle>
           <value>Common Stock</value>
         </underlyingSecurityTitle>
         <underlyingSecurityShares>
           <value>1006986</value>
         </underlyingSecurityShares>
      </underlyingSecurity>
      <postTransactionAmounts>
         <sharesOwnedFollowingTransaction>
           <value>23002065</value>
            <footnoteId id="F7"/>
            <footnoteId id="F8"/>
         </sharesOwnedFollowingTransaction>
      </postTransactionAmounts>
      <ownershipNature>
         <directOrIndirectOwnership>
           <value>I</value>
         </directOrIndirectOwnership>
         <natureOfOwnership>
           <value>See Notes</value>
            <footnoteId id="F5"/>
            <footnoteId id="F6"/>
         </natureOfOwnership>
      </ownershipNature>
   </derivativeSecurity>
   <footnotes>
<footnote id="F1"> This number does not include the number from Column 9 in Table II</footnote>

<footnote id="F2"> 8,750 shares of stock are held by the reporting person's spouse. 4,000 shares of common stock are held by Kimberlin Family Partners, L.P., a Colorado limited partnership, of which the reporting person is the general partner. 448,717 shares of common stock are held by Kevin Kimberlin Partners, L.P., a Delaware limited partnership (&quot;KKP&quot;), of which the general partner is KKP Management LLC, of which the reporting person is the managing member. 6,535,792 shares of common stock are held by Cheshire Associates LLC, of which the reporting person is a related party.</footnote>

<footnote id="F3"> 2,485,880 shares of the Issuer's common stock are held collectively by Spencer Trask Private Equity Fund I, Spencer Trask Private Equity Fund II and Spencer Trask Private Equity/Accredited Fund III, LLC (collectively, the &quot;Funds&quot;). The reporting person is approximately an 80% owner of the entity that is a 100% owner of the manager of such Funds.</footnote>

<footnote id="F4"> The reporting person disclaims beneficial ownership of the 2,485,880 shares of the Issuer's common stock held by the Funds except to the extent of the reporting person's pecuniary interest therein. In filing this Form 4 and reporting the information contained herein, the undersigned is not admitting to or conceding beneficial ownership of the 2,485,880 shares of common stock pursuant to Sections 13 or 16 of the Securities Exchange Act of 1934, as amended, or any rule or regulation promulgated thereunder.</footnote>

<footnote id="F5"> On July 7, 2003, Cheshire Associates LLC, of which the reporting person is a related party, exercised 1,774,888 Class A warrants in accordance with the revised terms for certain holders of shares of common stock and Class A warrants issued by the Issuer in connection with its December 2002 private placement. Upon exercise of the Class A warrants, Cheshire Associates LLC received 2,662,332 shares of common stock and 1,774,888 Class B warrants of the Issuer. Cheshire Associates LLC satisfied the payment of the aggregate exercise price for its exercise of the 1,774,888 Class A warrants (i.e., $2,360,601) by means of its partial cancellation and surrender of the $3,805,260.27 8% Convertible Secured Promissory Note issued by IRC in favor of Cheshire on 6/10/03.</footnote>

<footnote id="F6"> On July 7, 2003, Cheshire Associates LLC also purchased a $1,467,178.03 promissory note initially convertible into 1,006,986 shares of the Issuer's common stock. Such note was issued in consideration for the partial cancellation and surrender of the $3,805,260.27 8% Convertible Secured Promissory Note issued by IRC in favor of Cheshire on 6/10/03.</footnote>

<footnote id="F7"> This number includes the number of shares of the Issuer's common stock underlying options, convertible notes and warrants held by the reporting person or related parties of the reporting person, including 994,352 shares of common stock underlying the Class B warrants held by the Funds.</footnote>

<footnote id="F8"> The reporting person disclaims beneficial ownership of the 994,352 shares of the Issuer's common stock underlying the Class B warrants held by the Funds except to the extent of the reporting person's pecuniary interest therein. In filing this Form 4 and reporting the information contained herein, the undersigned is not admitting to or conceding beneficial ownership of the 994,352 shares of common stock pursuant to Sections 13 or 16 of the Securities Exchange Act of 1934, as amended, or any rule or regulation promulgated thereunder.</footnote>
   </footnotes>
   <ownerSignature>
      <signatureName>/s/ KEVIN B. KIMBERLIN</signatureName>
      <signatureDate>2003-07-11</signatureDate>
   </ownerSignature>
</ownershipDocument>

</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----