-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
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 GAPD50Te1B9JrpUCX1Dbrw==

<SEC-DOCUMENT>0000898432-03-000544.txt : 20030723
<SEC-HEADER>0000898432-03-000544.hdr.sgml : 20030723
<ACCEPTANCE-DATETIME>20030616152531
ACCESSION NUMBER:		0000898432-03-000544
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20030610
FILED AS OF DATE:		20030616

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			KIMBERLIN KEVIN
		CENTRAL INDEX KEY:			0000904841

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-18006
		FILM NUMBER:		03745513

	BUSINESS ADDRESS:	
		STREET 1:		SPENCER TRASK SECURITIES INC
		STREET 2:		535 MADISON AVENUE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		2123555565

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			IMMUNE RESPONSE CORP
		CENTRAL INDEX KEY:			0000817785
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				330255679
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		5935 DARWIN COURT
		CITY:			CARLSBAD
		STATE:			CA
		ZIP:			92008
		BUSINESS PHONE:		6194317080

	MAIL ADDRESS:	
		STREET 1:		5935 DARWIN COURT
		CITY:			CARLSBAD
		STATE:			CA
		ZIP:			92008
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>kimberlin-immune_4ex.xml
<TEXT>
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<!-- - EDGAR Ease Plus 1.0                                   04/22/03  TZ    -->
<ownershipDocument>
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    <documentType>4</documentType>
   <periodOfReport>2003-06-10</periodOfReport>
    <issuer>
        <issuerCik>0000817785</issuerCik>
        <issuerName>IMMUNE RESPONSE CORP</issuerName>
        <issuerTradingSymbol>IMNR</issuerTradingSymbol>
   </issuer>
   <reportingOwner>
      <reportingOwnerId>
            <rptOwnerCik>0000904841</rptOwnerCik>
            <rptOwnerName>KIMBERLIN KEVIN</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>  </rptOwnerStreet1>
            <rptOwnerStreet2>  </rptOwnerStreet2>
            <rptOwnerCity>  </rptOwnerCity>
            <rptOwnerState>  </rptOwnerState>
            <rptOwnerZipCode>  </rptOwnerZipCode>
        </reportingOwnerAddress>
            <reportingOwnerRelationship>
         <isDirector>1</isDirector>
         <isOfficer>0</isOfficer>
         <isTenPercentOwner>1</isTenPercentOwner>
         <isOther>0</isOther>
       </reportingOwnerRelationship>
   </reportingOwner>
   <nonDerivativeSecurity>
      <securityTitle>
         <value>Common Stock, par value $.0025 per share</value>
      </securityTitle>
      <transactionDate>
         <value>2003-06-10</value>
      </transactionDate>
      <transactionCoding>
         <transactionFormType>4</transactionFormType>
         <transactionCode>P</transactionCode>
         <equitySwapInvolved>0</equitySwapInvolved>
      </transactionCoding>
      <transactionAmounts>
         <transactionShares>
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         </transactionShares>
         <transactionValue>
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         </transactionValue>
         <transactionAcquiredDisposedCode>
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      <ownershipNature>
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         <natureOfOwnership>
            <value>See Note</value>
            <footnoteId id="F2"/>
         </natureOfOwnership>
      </ownershipNature>
   </nonDerivativeSecurity>
   <nonDerivativeSecurity>
      <securityTitle>
         <value>Common Stock, par value $.0025 per share</value>
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      <transactionDate>
         <value>2003-06-10</value>
      </transactionDate>
      <transactionCoding>
         <transactionFormType>4</transactionFormType>
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         <equitySwapInvolved>0</equitySwapInvolved>
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      <transactionAmounts>
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         </transactionShares>
         <transactionValue>
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         <transactionAcquiredDisposedCode>
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      </ownershipNature>
   </nonDerivativeSecurity>
   <nonDerivativeSecurity>
      <securityTitle>
         <value>Common Stock, par value $.0025 per share</value>
      </securityTitle>
      <transactionDate>
         <value>2003-06-10</value>
      </transactionDate>
      <transactionCoding>
         <transactionFormType>4</transactionFormType>
         <transactionCode>P</transactionCode>
         <equitySwapInvolved>0</equitySwapInvolved>
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      <transactionAmounts>
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         </transactionShares>
         <transactionValue>
           <value>1.457</value>
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         <transactionAcquiredDisposedCode>
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         <natureOfOwnership>
            <value>See Note</value>
            <footnoteId id="F2"/>
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      </ownershipNature>
   </nonDerivativeSecurity>
   <derivativeSecurity>
      <securityTitle>
         <value>8% Convertible Debenture due 2005</value>
      </securityTitle>
      <conversionOrExercisePrice>
         <value>3.5733</value>
      </conversionOrExercisePrice>
      <transactionDate>
         <value>2003-06-10</value>
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      <transactionCoding>
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            <footnoteId id="F4"/>
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         <transactionAcquiredDisposedCode>
           <value>D</value>
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            <footnoteId id="F4"/>
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      <exerciseDate>
         <value>2001-11-09</value>
            <footnoteId id="F6"/>
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      <expirationDate>
         <value>2003-06-10</value>
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      <underlyingSecurity>
         <underlyingSecurityTitle>
           <value>Common Stock</value>
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            <footnoteId id="F4"/>
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           <value>I</value>
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           <value>See Note</value>
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            <footnoteId id="F4"/>
         </natureOfOwnership>
      </ownershipNature>
   </derivativeSecurity>
   <derivativeSecurity>
      <securityTitle>
         <value>8% Convertible Debenture due 2005</value>
      </securityTitle>
      <conversionOrExercisePrice>
         <value>3.6082</value>
      </conversionOrExercisePrice>
      <transactionDate>
         <value>2003-06-10</value>
      </transactionDate>
      <transactionCoding>
         <transactionFormType>4</transactionFormType>
         <transactionCode>C</transactionCode>
         <equitySwapInvolved>0</equitySwapInvolved>
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      <transactionAmounts>
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         <transactionValue>
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            <footnoteId id="F4"/>
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         <transactionAcquiredDisposedCode>
           <value>D</value>
            <footnoteId id="F3"/>
            <footnoteId id="F4"/>
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      </transactionAmounts>
      <exerciseDate>
         <value>2002-02-14</value>
            <footnoteId id="F6"/>
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      <ownershipNature>
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            <footnoteId id="F4"/>
         </natureOfOwnership>
      </ownershipNature>
   </derivativeSecurity>
   <derivativeSecurity>
      <securityTitle>
         <value>8% Convertible Debenture due 2005</value>
      </securityTitle>
      <conversionOrExercisePrice>
         <value>1.470</value>
      </conversionOrExercisePrice>
      <transactionDate>
         <value>2003-06-10</value>
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         <transactionFormType>4</transactionFormType>
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            <footnoteId id="F4"/>
         </transactionAcquiredDisposedCode>
      </transactionAmounts>
      <exerciseDate>
         <value>2002-05-03</value>
            <footnoteId id="F6"/>
      </exerciseDate>
      <expirationDate>
         <value>2003-06-10</value>
            <footnoteId id="F6"/>
      </expirationDate>
      <underlyingSecurity>
         <underlyingSecurityTitle>
           <value>Common Stock</value>
         </underlyingSecurityTitle>
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           <value>0</value>
            <footnoteId id="F3"/>
            <footnoteId id="F4"/>
         </underlyingSecurityShares>
      </underlyingSecurity>
      <postTransactionAmounts>
         <sharesOwnedFollowingTransaction>
           <value>22184757</value>
            <footnoteId id="F5"/>
         </sharesOwnedFollowingTransaction>
      </postTransactionAmounts>
      <ownershipNature>
         <directOrIndirectOwnership>
           <value>I</value>
         </directOrIndirectOwnership>
         <natureOfOwnership>
           <value>See Note</value>
            <footnoteId id="F3"/>
            <footnoteId id="F4"/>
         </natureOfOwnership>
      </ownershipNature>
   </derivativeSecurity>
   <derivativeSecurity>
      <securityTitle>
         <value>8% Convertible Debenture due 2005</value>
      </securityTitle>
      <conversionOrExercisePrice>
         <value>1.4570</value>
      </conversionOrExercisePrice>
      <transactionDate>
         <value>2003-06-10</value>
      </transactionDate>
      <transactionCoding>
         <transactionFormType>4</transactionFormType>
         <transactionCode>P</transactionCode>
         <equitySwapInvolved>0</equitySwapInvolved>
      </transactionCoding>
      <transactionAmounts>
         <transactionShares>
           <value>2611709</value>
         </transactionShares>
         <transactionValue>
           <value>3805260</value>
            <footnoteId id="F3"/>
            <footnoteId id="F4"/>
         </transactionValue>
         <transactionAcquiredDisposedCode>
           <value>A</value>
            <footnoteId id="F3"/>
            <footnoteId id="F4"/>
         </transactionAcquiredDisposedCode>
      </transactionAmounts>
      <exerciseDate>
         <value>2003-06-10</value>
      </exerciseDate>
      <expirationDate>
         <value>2005-06-10</value>
      </expirationDate>
      <underlyingSecurity>
         <underlyingSecurityTitle>
           <value>Common Stock</value>
         </underlyingSecurityTitle>
         <underlyingSecurityShares>
           <value>2611709</value>
         </underlyingSecurityShares>
      </underlyingSecurity>
      <postTransactionAmounts>
         <sharesOwnedFollowingTransaction>
           <value>24796466</value>
            <footnoteId id="F5"/>
         </sharesOwnedFollowingTransaction>
      </postTransactionAmounts>
      <ownershipNature>
         <directOrIndirectOwnership>
           <value>I</value>
         </directOrIndirectOwnership>
         <natureOfOwnership>
           <value>See Note</value>
            <footnoteId id="F3"/>
            <footnoteId id="F4"/>
         </natureOfOwnership>
      </ownershipNature>
   </derivativeSecurity>
   <footnotes>
<footnote id="F1"> This number does not include the number from column 9 in table II.</footnote>

<footnote id="F2"> 8,750 shares of stock are held by the reporting person's spouse. 4,000 shares of common stock are held by Kimberlin Family Partners, L.P., a Colorado limited partnership, of which the reporting person is the general partner. 448,717 shares of common stock are held by Kevin Kimberlin Partners, L.P., a Delaware limited partnership (&quot;KKP&quot;), of which the general partner is KKP Management LLC, of which the reporting person is the managing member. 3,873,460 shares of common stock are held by Cheshire Associates LLC, of which the reporting person is a related party.</footnote>

<footnote id="F3"> On June 10, 2003, Cheshire Associates LLC, of which the reporting person is a related party, converted (a) the $2,000,000 principal amount of the 8% Convertible Secured Promissory Note, dated November 9, 2001, issued by the Company to KKP and subsequently contributed to Cheshire Associates LLC, plus accrued interest thereon, into 629,754 shares of common stock, (b) the $2,000,000 principal amount of the 8% Convertible Secured Promissory Note, dated February 14, 2002, issued by the Company to the Oshkim Limited Partnership (&quot;Oshkim&quot;), of which the reporting person is a related party, and subsequently contributed to Cheshire Associates LLC, plus accrued interest thereon, into 611,878 shares of common stock and (c) $541,917.81 of the principal amount of the 8% Convertible Secured Promissory Note, dated May 3, 2002, issued by the Company to Oshkim and subsequently contributed to Cheshire Associates LLC, into 371,940 shares of common stock.</footnote>

<footnote id="F4"> On June 10, 2003, Cheshire Associates LLC also purchased a promissory note initially convertible into 2,611,709 shares of the Issuer's common stock. Such note was issued in consideration for the partial conversion and subsequent cancellation of the 8% Convertible Secured Promissory Note, dated May 3, 2002.</footnote>

<footnote id="F5"> This number includes the number of shares of the Issuer's common stock underlying options, convertible notes and warrants held by the reporting person or related parties of the reporting person.</footnote>

<footnote id="F6"> This convertible secured promissory note has been converted.</footnote>
   </footnotes>
   <ownerSignature>
      <signatureName>/s/ Kevin B. Kimberlin</signatureName>
      <signatureDate>2003-06-16</signatureDate>
   </ownerSignature>
</ownershipDocument>

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</SEC-DOCUMENT>
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