LETTER 1 filename1.txt Via Facsimile and U.S. Mail Mail Stop 6010 February 22, 2006 Ms. Diane M. Barrett Vice President & Chief Financial Officer Noven Pharmaceuticals, Inc. 11960 S.W. 144th Street Miami, Florida 33186 Re: Noven Pharmaceuticals, Inc. Form 10-K for Fiscal Year Ended December 31, 2004 File No. 0-17254 Dear Ms. Barrett: We have completed our review of your Form 10-K and have no further comments at this time. Sincerely, Kevin Woody Branch Chief