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Commitments and Contingencies - Additional Information (Detail)
1 Months Ended 12 Months Ended
Dec. 09, 2015
USD ($)
Oct. 31, 2015
ft²
Sep. 30, 2015
Patent
Jul. 31, 2013
ft²
Mar. 31, 2016
USD ($)
ft²
Amendment
Mar. 31, 2015
USD ($)
Mar. 31, 2014
USD ($)
Apr. 30, 2016
USD ($)
Mar. 31, 2016
EUR (€)
ft²
Amendment
Dec. 31, 2015
USD ($)
Apr. 30, 2014
USD ($)
Commitments and Contingencies [Line Items]                      
Office space under operating lease | ft²         125,560       125,560    
Purchase price of property amount $ 16,500,000                    
Number of amendments | Amendment         2       2    
Rent expense         $ 2,400,000 $ 1,900,000 $ 1,500,000        
License agreement, upfront payment                   $ 500,000 $ 1,500,000
License agreement, maximum agreed additional payments upon achievement of development milestones                   2,000,000 $ 4,500,000
License agreement, milestone payment                   $ 600,000  
Payments obligations on achievement of certain development and regulatory milestones         3,000,000            
Patents allegedly infringed upon, number | Patent     2                
Subsequent Event                      
Commitments and Contingencies [Line Items]                      
License agreement, milestone payment               $ 500,000      
Europe                      
Commitments and Contingencies [Line Items]                      
Facilities leases, base rent per month         73,000       € 64,500    
Lease Agreements | Europe                      
Commitments and Contingencies [Line Items]                      
Office space under operating lease | ft²       33,000              
Lease, expiration date       Jul. 31, 2023              
Additional office space under operating lease | ft²   9,000                  
Lease Agreement Adjacent To Aachen Facility | Europe                      
Commitments and Contingencies [Line Items]                      
Office space under operating lease | ft²   30,000                  
Lease, expiration date   Jun. 30, 2016                  
For March 2016 through February 2018                      
Commitments and Contingencies [Line Items]                      
Facilities leases, base rent per month         84,914            
For March 2018 through February 2021                      
Commitments and Contingencies [Line Items]                      
Facilities leases, base rent per month         $ 87,530