Commitments and Contingencies - Additional Information (Detail)							0 Months Ended			1 Months Ended
	Dec. 31, 2014 USD ($)	Apr. 30, 2014 USD ($)	Dec. 31, 2014 For March 2014 through April 2014 USD ($)	Dec. 31, 2014 For May 2014 through February 2016 USD ($)	Dec. 31, 2014 For March 2016 through February 2018 USD ($)	Dec. 31, 2014 For March 2018 through February 2021 USD ($)	Jul. 01, 2014 ECP Entwicklungsgesellschaft mbH	Dec. 31, 2014 ECP Entwicklungsgesellschaft mbH USD ($)	Jul. 01, 2014 ECP Entwicklungsgesellschaft mbH USD ($)	Jul. 31, 2013 Europe Lease Agreements	Dec. 31, 2014 Europe Lease Agreements USD ($)	Dec. 31, 2014 Europe Lease Agreements EUR (€)
Commitments and Contingencies [Line Items]
Facilities leases, base rent per month			$ 66,000	$ 74,050	$ 70,750	$ 72,750					$ 42,000	€ 34,500
Lease, expiration date										Jul. 31, 2023
License agreement, upfront payment		1,500,000
License agreement, maximum agreed additional payments upon achievement of development milestones		4,500,000
Potential payouts payments									15,000,000
Period of milestone payment							20 years
Fair value of contingent consideration	$ 6,365,000							$ 6,365,000