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Condensed Consolidated Statements of Cash Flows - USD ($)
9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Operating activities:    
Net loss $ (5,279,210) $ (4,320,835)
Adjustments to reconcile net loss to net cash used in operating activities:    
Amortization and depreciation 4,765 4,964
Non-cash lease expense 89,686 82,500
Share-based compensation 174,268 229,076
Issuance of common stock to vendors for services   73,000
Issuance of common stock for purchase option   50,000
Loss on extinguishment of debt   393,791
Change in fair value of convertible debt (260,933) (387,537)
Amortization of deferred issuance costs associated with convertible debt   12,518
Change in operating assets and liabilities:    
Contracts and grants receivable 171,254 49,079
Prepaid expenses and other current assets 525,684 (310,229)
Research and development incentives receivable 51,879 92,092
Operating lease liability (89,969) (80,458)
Accounts payable and accrued expenses (1,391,432) (2,382,708)
Accrued compensation (166,753) (281,149)
Net cash flows from operating activities (6,170,761) (6,775,896)
Financing activities:    
Proceeds from issuance of common stock pursuant to At Market Issuance Sales Agreement 58,436 3,091,462
Proceeds from issuance of common stock and pre-funded warrants 4,741,400 8,495,817
Proceeds from the exercise of warrants 4,450,172 3,299
Issuance costs associated with warrant inducement (374,774)  
Convertible debt repayments (686,436) (7,000,000)
Net cash flows from financing activities 7,519,211 3,709,688
Effect of exchange rate on cash and cash equivalents 45,569 5,127
Net increase in cash and cash equivalents 1,394,019 (3,061,081)
Cash and cash equivalents at beginning of period 8,446,158 13,359,615
Cash and cash equivalents at end of period 9,840,177 10,298,534
Supplemental information:    
Cash paid for state income taxes 42,162 13,006
Cash paid for interest 183,771 488,011
Cash paid for lease liabilities:    
Operating lease 102,300 99,975
Non-cash investing and financing activities:    
Pontifax conversion of portion of debt principal into common stock 254,256  
Deferred issuance cost reclassified to additional paid-in capital 228,161 2,339
Redemption liability for Series D preferred stock   43
Offering costs included in accounts payable 83,810 46,180
Warrant modification - incremental value 7,177,683  
At Market Issuance Sales Agreement    
Financing activities:    
Stock issuance costs associated (44,522) (93,009)
Public Offering    
Financing activities:    
Stock issuance costs associated $ (625,065) $ (787,881)