Consolidated Statements of Cash Flows - USD ($)	6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022
Operating activities:
Net loss	$ (2,658,133)	$ (6,735,781)
Adjustments to reconcile net loss to net cash used in operating activities:
Amortization and depreciation	3,375	16,744
Non-cash lease expense	54,432	60,475
Share-based compensation	163,676	149,941
Issuance of common stock to vendors for services	73,000	100,001
Issuance of common stock to Silk Roads for purchase option	50,000
Loss on extinguishment of debt	393,791
Change in fair value of convertible debt	(460,000)
Amortization of deferred issuance costs associated with convertible debt	12,518	20,598
Change in operating assets and liabilities:
Licensing, contracts and grants receivable	1,374	(182,890)
Prepaid expenses and other current assets	102,882	45,768
Research and development incentives receivable	93,821	70,335
Operating lease liability	(53,071)	(60,244)
Deferred revenue		200,000
Accounts payable and accrued expenses	(1,604,414)	793,324
Accrued compensation	(262,831)	(245,174)
Net cash used in operating activities	(4,089,580)	(5,766,903)
Investing activities:
Purchases of office furniture and equipment		(13,073)
Net cash used in investing activities		(13,073)
Financing activities:
Proceeds from issuance of common stock pursuant to B. Riley At Market Issuance Sales Agreement	3,091,462
Proceeds from issuance of common stock and pre-funded warrants pursuant to public offering	8,495,817
Convertible debt repayments	(7,000,000)
Net cash provided by financing activities	3,884,958
Effect of exchange rate on cash and cash equivalents	5,946	(106,229)
Net decrease in cash and cash equivalents	(198,676)	(5,886,205)
Cash and cash equivalents at beginning of period	13,359,615	26,043,897
Cash and cash equivalents at end of period	13,160,939	20,157,692
Supplemental information:
Cash paid for state income taxes	10,879	5,600
Cash paid for interest	424,660	432,751
Cash paid for lease liabilities:
Operating lease	66,650	66,650
Non-cash investing and financing activities:
Right-of-use assets and lease liabilities recorded		$ 347,546
Deferred issuance cost reclassified to additional paid-in capital	2,339
Redemption liability for Series D preferred stock	43
Stock issuance costs included in accounts payable	221,450
B. Riley Sales Agreement
Financing activities:
Stock issuance costs associated	(93,009)
Public Offering
Financing activities:
Stock issuance costs associated	(612,611)
Pre-funded warrants
Financing activities:
Proceeds from the exercise of pre-funded warrants	$ 3,299