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Nature of Business (Details)
3 Months Ended 6 Months Ended
Aug. 14, 2023
USD ($)
$ / shares
shares
May 09, 2023
USD ($)
$ / shares
shares
May 02, 2023
$ / shares
shares
Apr. 27, 2023
shares
Feb. 10, 2023
Feb. 09, 2023
shares
Jun. 30, 2023
USD ($)
shares
Jun. 30, 2022
USD ($)
Jun. 30, 2023
USD ($)
segment
shares
Jun. 30, 2022
USD ($)
Dec. 31, 2022
USD ($)
shares
Dec. 31, 2021
USD ($)
Nature of business:                        
Number of operating segments | segment                 2      
Accumulated deficit             $ (222,221,579)   $ (222,221,579)   $ (219,563,446)  
Net loss             (1,612,024) $ (2,386,760) (2,658,133) $ (6,735,781)    
Net cash used in operating activities                 (4,089,580) (5,766,903)    
Reclassification of convertible debt from current to non-current liability             2,094,000   2,094,000      
Number of shares sold             3,020,732   3,091,462      
Cash and cash equivalents             13,160,939 20,157,692 13,160,939 20,157,692 13,359,615 $ 26,043,897
Net decrease in cash                 $ 198,676 5,886,205    
Percentage change in cash and cash equivalent                 1.00%      
Accumulated deficit             222,221,579   $ 222,221,579   219,563,446  
Working capital             7,713,536   7,713,536   (2,663,721)  
Working capital increase, decrease                 $ (10,377,257)      
Working capital increase (decrease) as a percent                 390.00%      
Government grant funding             $ 113,756   $ 113,756   $ 115,130  
Common Stock, Shares, Issued | shares             9,841,854   9,841,854   2,908,578  
Number of shares issued | shares       50,000                
Reverse stock spilt effective from February 10, 2023         0.067 0.067            
Fractional shares issue under reverse stock split | shares           0            
Repayment of debt principal                 $ 7,000,000      
Consideration paid recorded in general and administrative expense             $ 890,533 $ 1,382,793 2,125,909 $ 3,924,261    
Issuance of common stock in connection with Silk Roads purchase option             50,000   50,000      
Public Offering                        
Nature of business:                        
Proceeds from Issuance of Common Stock   $ 8,500,000                    
Shares issued price per share | $ / shares   $ 1.30                    
Exercise price of warrants | $ / shares   $ 0.001                    
Expiration term of warrants   5 years                    
B. Riley Sales Agreement                        
Nature of business:                        
Proceeds from Issuance of Common Stock                 7,700,000      
Number of shares sold                 3,000,000      
Common Stock                        
Nature of business:                        
Number of shares sold             $ 830   $ 851      
Issuance of common stock in connection with Silk Roads purchase option (in shares) | shares             31,646   31,646      
Issuance of common stock in connection with Silk Roads purchase option             $ 32   $ 32      
Common Stock | Public Offering                        
Nature of business:                        
Shares issued price per share | $ / shares   $ 1.30                    
Number of shares issued | shares   2,301,500                    
Exercise price of warrants | $ / shares   $ 1.50                    
Pre-funded warrants | Public Offering                        
Nature of business:                        
Number of common warrants to purchase shares issued | shares   4,237,000                    
Common warrants | Public Offering                        
Nature of business:                        
Number of common warrants to purchase shares issued | shares   6,538,500                    
Exercise price of warrants | $ / shares   $ 1.50                    
CiVax                        
Nature of business:                        
Revenue from collaborative arrangement                 $ 1,500,000      
Term (in years)                 P2Y      
HyBryte                        
Nature of business:                        
Revenue from collaborative arrangement                 $ 1,100,000      
Term (in years)                 P4Y      
NIH                        
Nature of business:                        
Government grant funding             1,100,000   $ 1,100,000      
Exclusive option agreement | Silk Road                        
Nature of business:                        
Consideration paid recorded in general and administrative expense             $ 50,000   $ 50,000      
Exclusive option agreement | Common Stock                        
Nature of business:                        
Shares issued price per share | $ / shares     $ 1.58                  
Number of shares issued | shares     31,646                  
Exclusive option agreement | Common Stock | Silk Road                        
Nature of business:                        
Issuance of common stock in connection with Silk Roads purchase option (in shares) | shares             31,646   31,646      
Issuance of common stock in connection with Silk Roads purchase option             $ 50,000   $ 50,000      
B Riley Sales Agreement [Member] | Underwritten public offering                        
Nature of business:                        
Maximum Percentage Of Shares Available For Sale Of Market Value 33.33%                      
B Riley Sales Agreement [Member] | Subsequent Event                        
Nature of business:                        
Proceeds from Issuance of Common Stock $ 3,091,462                      
Common stock available for sale (in Dollars) $ 23,600,000                      
Maximum Percentage Of Shares Available For Sale Of Market Value 33.33%                      
Shares issued price per share | $ / shares $ 3.63                      
Common Stock, Shares, Issued | shares 851,130