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Consolidated Statements of Cash Flows (Unaudited) - USD ($)
9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Operating activities:    
Net loss $ (10,044,784) $ (7,847,097)
Adjustments to reconcile net loss to net cash used in operating activities:    
Amortization and depreciation 21,538 26,614
Non-cash lease expense 86,326 86,124
Share-based compensation 220,656 255,147
Issuance of common stock to vendors for services 150,002 27,500
Amortization of deferred issuance costs associated with convertible debt 31,068 31,456
Gain on forgiveness of PPP loan   (421,584)
Change in operating assets and liabilities:    
Licensing, contracts and grants receivable 8,147 159,590
Prepaid expenses and other current assets (113,452) (203,619)
Research and development incentives receivable 67,912 258,509
Operating lease liability (85,415) (86,124)
Deferred revenue 200,000  
Accounts payable and accrued expenses 679,268 (154,415)
Accrued compensation (243,146) (816,367)
Net cash used in operating activities (9,021,880) (8,684,266)
Investing activities:    
Purchases of office furniture and equipment (13,073)  
Net cash used in investing activities (13,073)  
Financing activities:    
Proceeds from issuance of common stock pursuant to B. Riley At Market Issuance Sales Agreement   19,417,290
Costs associated with B. Riley At Market Issuance Sales Agreement   (584,334)
Proceeds from the exercise of warrants   51
Proceeds from the exercises of stock options   25,835
Costs associated with issuance of convertible debt   (45,512)
Principal repayment - financing lease   (6,149)
Net cash provided by financing activities   18,807,181
Effect of exchange rate on cash and cash equivalents (143,302) 67,909
Net (decrease)/increase in cash and cash equivalents (9,178,255) 10,190,824
Cash and cash equivalents at beginning of period 26,043,897 18,676,663
Cash and cash equivalents at end of period 16,865,642 28,867,487
Supplemental information:    
Cash paid for state income taxes 13,243 7,382
Cash paid for interest 643,921 444,814
Cash paid for lease liabilities:    
Operating lease 99,975 99,975
Financing lease   6,408
Non-cash activities:    
Right-of-use assets and lease liabilities recorded $ 347,546  
Deferred issuance cost in accounts payable   22,700
Deferred issuance cost reclassified to additional paid-in capital   $ 55,572