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Consolidated Statements of Changes in Shareholders' Equity (Unaudited) - USD ($)
Common Stock
Additional Paid-In Capital
Accumulated Other Comprehensive Income/Loss
Accumulated Deficit
Total
Balance at Dec. 31, 2020 $ 30,644 $ 196,949,655 $ (24,337) $ (193,214,134) $ 3,741,828
Balance (in shares) at Dec. 31, 2020 30,643,656        
Issuance of common stock pursuant to B. Riley At Market Issuance Sales Agreement $ 11,931 19,405,359     19,417,290
Issuance of common stock pursuant to B. Riley At Market Issuance Sales Agreement (in shares) 11,931,513        
Issuance costs associated with B. Riley At Market Issuance Sales Agreement   (639,906)     (639,906)
Issuance of common stock to vendors $ 25 27,475     27,500
Issuance of common stock to vendors (in shares) 25,000        
Exercise of common stock options $ 30 25,805     25,835
Exercise of common stock options (in shares) 30,254        
Exercise of warrants   51     51
Exercise of warrants (in shares) 13        
Share-based compensation expense   255,147     255,147
Foreign currency translation adjustment     73,895   73,895
Net loss       (7,847,097) (7,847,097)
Balance at Sep. 30, 2021 $ 42,630 216,023,586 49,558 (201,061,231) 15,054,543
Balance (in Shares) at Sep. 30, 2021 42,630,436        
Balance at Jun. 30, 2021 $ 40,079 213,061,849 (32,058) (197,473,680) 15,596,190
Balance (in shares) at Jun. 30, 2021 40,078,760        
Issuance of common stock pursuant to B. Riley At Market Issuance Sales Agreement $ 2,496 2,924,465     2,926,961
Issuance of common stock pursuant to B. Riley At Market Issuance Sales Agreement (in shares) 2,496,422        
Issuance costs associated with B. Riley At Market Issuance Sales Agreement   (95,729)     (95,729)
Issuance of common stock to vendors $ 25 27,475     27,500
Issuance of common stock to vendors (in shares) 25,000        
Exercise of common stock options $ 30 25,805     25,835
Exercise of common stock options (in shares) 30,254        
Share-based compensation expense   79,721     79,721
Foreign currency translation adjustment     81,616   81,616
Net loss       (3,587,551) (3,587,551)
Balance at Sep. 30, 2021 $ 42,630 216,023,586 49,558 (201,061,231) 15,054,543
Balance (in Shares) at Sep. 30, 2021 42,630,436        
Balance at Dec. 31, 2021 $ 42,873 216,402,890 41,942 (205,765,107) 10,722,598
Balance (in shares) at Dec. 31, 2021 42,873,445        
Issuance of common stock to vendors $ 232 149,770     150,002
Issuance of common stock to vendors (in shares) 231,746        
Share-based compensation expense   220,656     220,656
Foreign currency translation adjustment     (16,470)   (16,470)
Net loss       (10,044,784) (10,044,784)
Balance at Sep. 30, 2022 $ 43,105 216,773,316 25,472 (215,809,891) 1,032,002
Balance (in Shares) at Sep. 30, 2022 43,105,191        
Balance at Jun. 30, 2022 $ 43,050 216,652,655 11,069 (212,500,888) 4,205,886
Balance (in shares) at Jun. 30, 2022 43,050,245        
Issuance of common stock to vendors $ 55 49,946     50,001
Issuance of common stock to vendors (in shares) 54,946        
Share-based compensation expense   70,715     70,715
Foreign currency translation adjustment     14,403   14,403
Net loss       (3,309,003) (3,309,003)
Balance at Sep. 30, 2022 $ 43,105 $ 216,773,316 $ 25,472 $ (215,809,891) $ 1,032,002
Balance (in Shares) at Sep. 30, 2022 43,105,191