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Consolidated Statements of Cash Flows (Unaudited) - USD ($)
6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Operating activities:    
Net loss $ (6,735,781) $ (4,259,546)
Adjustments to reconcile net loss to net cash used in operating activities:    
Amortization and depreciation 16,744 17,739
Non-cash lease expense 60,475 56,698
Share-based compensation 149,941 175,426
Issuance of common stock to vendors for services 100,001  
Amortization of deferred issuance costs associated with convertible debt 20,598 20,986
Gain on forgiveness of PPP loan   (421,584)
Change in operating assets and liabilities:    
Licensing, contracts and grants receivable (182,890) 86,094
Prepaid expenses and other current assets 45,768 76,879
Research and development incentives receivable 70,335 306,651
Operating lease liability (60,244) (56,698)
Deferred revenue 200,000  
Accounts payable and accrued expenses 793,324 (838,749)
Accrued compensation (245,174) (808,043)
Net cash used in operating activities (5,766,903) (5,644,147)
Investing activities:    
Purchases of office furniture and equipment (13,073)  
Net cash used in investing activities (13,073)  
Financing activities:    
Proceeds from issuance of common stock pursuant to B. Riley At Market Issuance Sales Agreement   16,490,329
Costs associated with B. Riley At Market Issuance Sales Agreement   (496,450)
Proceeds from the exercise of warrants   51
Costs associated with issuance of convertible debt   (45,512)
Principal repayment - financing lease   (4,048)
Net cash provided by financing activities   15,944,370
Effect of exchange rate on cash and cash equivalents (106,229) 3,083
Net (decrease)/increase in cash and cash equivalents (5,886,205) 10,303,306
Cash and cash equivalents at beginning of period 26,043,897 18,676,663
Cash and cash equivalents at end of period 20,157,692 28,979,969
Supplemental information:    
Cash paid for state income taxes 5,600 7,382
Cash paid for interest 432,751 444,814
Cash paid for lease liabilities:    
Operating lease 66,650 66,650
Financing lease   4,272
Non-cash activities:    
Right-of-use assets and lease liabilities recorded $ 347,546  
Deferred issuance cost reclassified to additional paid-in capital   $ 47,727