Consolidated Statements of Changes in Shareholders' Equity (Unaudited) - USD ($)	Common Stock	Additional Paid-In Capital	Accumulated Other Comprehensive Income/Loss	Accumulated Deficit	Total
Balance at Dec. 31, 2020	$ 30,644	$ 196,949,655	$ (24,337)	$ (193,214,134)	$ 3,741,828
Balance (in shares) at Dec. 31, 2020	30,643,656
Issuance of common stock pursuant to B. Riley At Market Issuance Sales Agreement	$ 9,376	16,386,230			16,395,606
Issuance of common stock pursuant to B. Riley At Market Issuance Sales Agreement (in shares)	9,376,792
Issuance costs associated with B. Riley At Market Issuance Sales Agreement		(539,897)			(539,897)
Exercise of common stock options		51			51
Exercise of common stock options (in shares)	13
Share-based compensation expense		94,805			94,805
Foreign currency translation adjustment			(11,338)		(11,338)
Net loss				(2,362,478)	(2,362,478)
Balance at Mar. 31, 2021	$ 40,020	212,890,844	(35,675)	(195,576,612)	17,318,577
Balance (in Shares) at Mar. 31, 2021	40,020,461
Balance at Dec. 31, 2021	$ 42,873	216,402,890	41,942	(205,765,107)	10,722,598
Balance (in shares) at Dec. 31, 2021	42,873,445
Issuance of common stock to vendors	$ 81	49,920			50,001
Issuance of common stock to vendors (in shares)	80,646
Share-based compensation expense		78,271			78,271
Foreign currency translation adjustment			82,650		82,650
Net loss				(4,349,021)	(4,349,021)
Balance at Mar. 31, 2022	$ 42,954	$ 216,531,081	$ 124,592	$ (210,114,128)	$ 6,584,499
Balance (in Shares) at Mar. 31, 2022	42,954,091