Accrued Expenses (Details) - USD ($)	Mar. 31, 2022	Dec. 31, 2021	Mar. 31, 2021
Accrued Expenses
Clinical trail expenses	$ 1,997,721		$ 2,625,779
Other	594,575		330,766
Accrued expenses	$ 2,592,296	$ 2,956,545	$ 2,956,545