Consolidated Statements of Cash Flows - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Operating activities:
Net loss	$ (12,550,973)	$ (17,688,522)
Adjustments to reconcile net loss to net cash used in operating activities:
Amortization and depreciation	34,161	62,372
Non-cash lease expense	116,290	130,670
Share-based compensation	361,559	409,933
Issuance of common stock for milestone		5,000,000
Issuance of common stock to vendors	27,500	59,000
Deferred issuance costs written off		61,609
Amortization of deferred issuance costs associated with convertible debt	41,926	1,205
Gain on forgiveness of PPP loan	(421,584)
Change in operating assets and liabilities:
Contracts and grants receivable	64,885	815,061
Prepaid expenses and other current assets	(57,430)	384,424
Security deposit		(20)
Research and development incentives receivable	205,237	21,924
Operating lease liability	(116,290)	(131,845)
Accounts payable and accrued expenses	1,127,259	(1,157,160)
Accrued compensation	(572,160)	576,923
Net cash used in operating activities	(11,739,620)	(11,454,426)
Investing activities:
Purchases of office furniture and equipment	(11,789)	(7,147)
Net cash used in investing activities	(11,789)	(7,147)
Financing activities:
Proceeds from issuance of common stock pursuant to B. Riley At Market Issuance Sales Agreement	19,705,647	14,198,160
Costs associated with B. Riley At Market Issuance Sales Agreement	(621,899)	(656,264)
Proceeds from the exercise of warrants	79	860,918
Proceeds from the exercises of stock options	25,835	4,987
Proceeds from Convertible Debt		10,000,000
Costs associated with issuance of convertible debt	(45,512)	(141,466)
Principal repayment - financing lease	(6,149)	(7,516)
Proceeds from paycheck protection program		417,830
Net cash provided by financing activities	19,058,001	24,676,649
Effect of exchange rate on cash and cash equivalents	60,642	40,879
Net increase in cash and cash equivalents	7,367,234	13,255,955
Cash and cash equivalents at beginning of period	18,676,663	5,420,708
Cash and cash equivalents at end of period	26,043,897	18,676,663
Supplemental information:
Cash paid for state income taxes	7,727	4,021
Cash paid for interest	668,715	34,406
Cash paid for lease liabilities:
Operating lease	133,300	141,050
Financing lease	6,408	8,544
Right-of use assets and lease liabilities recorded		240,727
Deferred issuance cost reclassified to additional-paid-in capital	$ 33,257	$ 67,733