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Nature of Business (Details)	12 Months Ended
Nature of Business (Details)	Dec. 31, 2021 USD ($) segment	Dec. 31, 2020 USD ($)	Aug. 13, 2021 USD ($)
Nature of Business
Number of operating segments \| segment	2
Accumulated deficit	$ (205,765,107)	$ (193,214,134)
Net loss	(12,550,973)	(17,688,522)
Net cash used in operating activities	(11,739,620)	(11,454,426)
Cash and cash equivalents	26,043,897	18,676,663
Increase of cash and cash equivalents		$ 7,367,234
Percentage change in cash and cash equivalent		39.00%
Working capital	$ 20,278,345	$ 13,386,485
Working capital increase (decrease) as a percent	51.00%
Contracts and grants receivable	$ 138,889	$ 203,774
FBR Sales Agreement [Member]
Nature of Business
Borrowing Capacity			$ 26,800,000
CiVax
Nature of Business
Term (in years)	two years
Subcontract revenue	$ 1,500,000
NIH
Nature of Business
Contracts and grants receivable	$ 1,350,000
NIAID \| Contract revenue
Nature of Business
Term (in years)	five years
Subcontract revenue	$ 700,000
DTRA \| Contract revenue
Nature of Business
Term (in years)	three years
Subcontract revenue	$ 600,000