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Summary of Significant Accounting Policies - Loss per share (Details) - shares
9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Securities excluded 7,728,354 7,437,521
Common stock purchase warrants    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Securities excluded 5,731,464 5,886,817
Stock options    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Securities excluded 1,996,890 1,550,704