Consolidated Statements of Changes in Shareholders' Equity (Unaudited) - USD ($)	Common Stock	Additional Paid-In Capital	Acculated other comprehensive loss	Accumulated Deficit	Total
Balance at Dec. 31, 2019	$ 21,753	$ 177,006,004	$ (45,010)	$ (175,525,612)	$ 1,457,135
Balance (in shares) at Dec. 31, 2019	21,753,124
Issuance of common stock pursuant to FBR at Market Issuance	$ 4,545	9,455,404			9,459,949
Issuance of common stock pursuant to FBR at Market Issuance (in shares)	4,545,116
Issuance costs associated with FBR at Market Issuance Sales Agreement		(425,524)			(425,524)
Issuance of common stock for milestone	$ 1,956	4,998,044			5,000,000
Issuance of common stock for milestone (in shares)	1,956,182
Issuance of common stock to vendor	$ 30	58,970			59,000
Issuance of common stock to vendor (in shares)	30,000
Exercise of common stock options	$ 2				2
Options exercised (in shares)	2,189
Excerise of warrants	$ 305	685,079			685,384
Exercise of warrants (in shares)	304,821
Share-based compensation expense		144,694			144,694
Foreign currency translation adjustment			8,059		8,059
Net loss				(10,358,097)	(10,358,097)
Balance at Jun. 30, 2020	$ 28,591	191,922,671	(36,951)	(185,883,709)	6,030,602
Balance (in Shares) at Jun. 30, 2020	28,591,432
Balance at Mar. 31, 2020	$ 25,778	186,624,561	(28,767)	(183,106,946)	3,514,626
Balance (in shares) at Mar. 31, 2020	25,778,431
Issuance of common stock pursuant to FBR at Market Issuance	$ 2,813	5,467,910			5,470,723
Issuance of common stock pursuant to FBR at Market Issuance (in shares)	2,813,001
Issuance costs associated with FBR at Market Issuance Sales Agreement		(250,803)			(250,803)
Share-based compensation expense		81,003			81,003
Foreign currency translation adjustment			(8,184)		(8,184)
Net loss				(2,776,763)	(2,776,763)
Balance at Jun. 30, 2020	$ 28,591	191,922,671	(36,951)	(185,883,709)	6,030,602
Balance (in Shares) at Jun. 30, 2020	28,591,432
Balance at Dec. 31, 2020	$ 30,644	196,949,655	(24,337)	(193,214,134)	3,741,828
Balance (in shares) at Dec. 31, 2020	30,643,656
Issuance of common stock pursuant to FBR at Market Issuance	$ 9,435	16,480,894			16,490,329
Issuance of common stock pursuant to FBR at Market Issuance (in shares)	9,435,091
Issuance costs associated with FBR at Market Issuance Sales Agreement		(544,177)			(544,177)
Excerise of warrants		51			51
Exercise of warrants (in shares)	13
Share-based compensation expense		175,426			175,426
Foreign currency translation adjustment			(7,721)		(7,721)
Net loss				(4,259,546)	(4,259,546)
Balance at Jun. 30, 2021	$ 40,079	213,061,849	(32,058)	(197,473,680)	15,596,190
Balance (in Shares) at Jun. 30, 2021	40,078,760
Balance at Mar. 31, 2021	$ 40,020	212,890,844	(35,675)	(195,576,612)	17,318,577
Balance (in shares) at Mar. 31, 2021	40,020,461
Issuance of common stock pursuant to FBR at Market Issuance	$ 59	94,664			94,723
Issuance of common stock pursuant to FBR at Market Issuance (in shares)	58,299
Issuance costs associated with FBR at Market Issuance Sales Agreement		(4,280)			(4,280)
Share-based compensation expense		80,621			80,621
Foreign currency translation adjustment			3,617		3,617
Net loss				(1,897,068)	(1,897,068)
Balance at Jun. 30, 2021	$ 40,079	$ 213,061,849	$ (32,058)	$ (197,473,680)	$ 15,596,190
Balance (in Shares) at Jun. 30, 2021	40,078,760