Stock Option Plans and Warrants to Purchase Common Stock (Details) - Schedule of activity under the 2005 plan and the 2015 plan - $ / shares	12 Months Ended
	Dec. 31, 2020	Dec. 31, 2019
Schedule of activity under the 2005 plan and the 2015 plan [Abstract]
Options outstanding beginning balance	1,506,972	1,022,095
Weighted Average Options Exercise Price outstanding beginning balance	$ 3.77	$ 5.32
Options outstanding ending balance	1,933,804	1,506,972
Weighted Average Options Exercise Price outstanding ending balance	$ 2.96	$ 3.77
Options Granted	520,812	596,740
Weighted Average Options Exercise Price Granted	$ 2.17	$ 1.09
Options Forfeited	(88,222)	(111,863)
Weighted Average Options Exercise Price Forfeited	$ 13.06	$ 3.27
Options Exercised	(5,758)
Weighted Average Options Exercise Price Exercised	$ 1.19