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Consolidated Statements of Changes in Shareholders' Equity (Unaudited) - USD ($)
Common Stock
Additional Paid-In Capital
Accumulated Other Comprehensive Loss
Accumulated Deficit
Total
Balance at Dec. 31, 2018 $ 17,683 $ 172,436,176 $ (3,669) $ (166,170,020) $ 6,280,170
Balance (in Shares) at Dec. 31, 2018 17,682,839        
Issuance of common stock pursuant to FBR At Market Sales Issuance Agreement $ 861 841,383 842,244
Issuance of common stock pursuant to FBR At Market Sales Issuance Agreement (in Shares) 861,352        
Issuance costs associated with FBR At Market Sales Issuance Agreement (33,215) (33,215)
Issuance of common stock to vendors $ 197 160,860 161,057
Issuance of common stock to vendors (in Shares) 197,019        
Share-based compensation expense 152,465 152,465
Foreign currency translation adjustment (3,339) (3,339)
Net loss (3,763,148) (3,763,148)
Balance at Jun. 30, 2019 $ 18,741 173,557,669 (7,008) (169,933,168) 3,636,234
Balance (in Shares) at Jun. 30, 2019 18,741,210        
Balance at Mar. 31, 2019 $ 18,189 173,076,044 (3,020) (167,809,647) 5,281,566
Balance (in Shares) at Mar. 31, 2019 18,189,208        
Issuance of common stock pursuant to FBR At Market Sales Issuance Agreement $ 415 319,245 319,660
Issuance of common stock pursuant to FBR At Market Sales Issuance Agreement (in Shares) 414,983        
Issuance costs associated with FBR At Market Sales Issuance Agreement (13,832) (13,832)
Issuance of common stock to vendors $ 137 103,320 103,457
Issuance of common stock to vendors (in Shares) 137,019        
Share-based compensation expense 72,892 72,892
Foreign currency translation adjustment (3,988) (3,988)
Net loss (2,123,521) (2,123,521)
Balance at Jun. 30, 2019 $ 18,741 173,557,669 (7,008) (169,933,168) 3,636,234
Balance (in Shares) at Jun. 30, 2019 18,741,210        
Balance at Dec. 31, 2019 $ 21,753 177,006,004 (45,010) (175,525,612) 1,457,135
Balance (in Shares) at Dec. 31, 2019 21,753,124        
Issuance of common stock pursuant to FBR At Market Sales Issuance Agreement $ 4,545 9,455,404 9,459,949
Issuance of common stock pursuant to FBR At Market Sales Issuance Agreement (in Shares) 4,545,116        
Issuance costs associated with FBR At Market Sales Issuance Agreement (425,524) (425,524)
Issuance of common stock for milestone $ 1,956 4,998,044     5,000,000
Issuance of common stock for milestone (in Shares) 1,956,182        
Issuance of common stock to vendors $ 30 58,970 59,000
Issuance of common stock to vendors (in Shares) 30,000        
Exercise of common stock options $ 2     2
Exercise of common stock options (in Shares) 2,189        
Exercise of warrants $ 305 685,079     685,384
Exercise of warrants (in Shares) 304,821        
Share-based compensation expense 144,694 144,694
Foreign currency translation adjustment 8,059 8,059
Net loss (10,358,097) (10,358,097)
Balance at Jun. 30, 2020 $ 28,591 191,922,671 (36,951) (185,883,709) 6,030,602
Balance (in Shares) at Jun. 30, 2020 28,591,432        
Balance at Mar. 31, 2020 $ 25,778 186,624,561 (28,767) (183,106,946) 3,514,626
Balance (in Shares) at Mar. 31, 2020 25,778,431        
Issuance of common stock pursuant to FBR At Market Sales Issuance Agreement $ 2,813 5,467,910 5,470,723
Issuance of common stock pursuant to FBR At Market Sales Issuance Agreement (in Shares) 2,813,001        
Issuance costs associated with FBR At Market Sales Issuance Agreement (250,803) (250,803)
Share-based compensation expense 81,003 81,003
Foreign currency translation adjustment (8,184) (8,184)
Net loss (2,776,763) (2,776,763)
Balance at Jun. 30, 2020 $ 28,591 $ 191,922,671 $ (36,951) $ (185,883,709) $ 6,030,602
Balance (in Shares) at Jun. 30, 2020 28,591,432