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Consolidated Statements of Cash Flows - USD ($)
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Operating activities:    
Net loss $ (9,355,592) $ (8,899,975)
Adjustments to reconcile net loss to net cash used in operating activities:    
Amortization and depreciation 54,450 44,060
Noncash lease expense 123,110  
Share-based compensation 376,339 380,886
Issuance of common stock for services 159,238
(Gain) loss on disposition of office furniture (3,843) 1,483
Change in operating assets and liabilities:    
Contracts and grants receivable 182,880 (275,464)
Prepaid expenses and other current assets (452,255) 105,976
Security deposit (23)
UK research and development incentives receivable (444,043)
Tax receivable 416,810
Operating lease liability (121,938)  
Accounts payable and accrued expenses 1,968,565 1,019,984
Accrued compensation 3,545 (38,391)
Total adjustments 1,846,025 1,655,344
Net cash used in operating activities (7,509,567) (7,244,631)
Investing activities:    
Purchases of office furniture and equipment (30,209) (1,925)
Proceeds from sale of office furniture 5,500 1,000
Net cash used in investing activities (24,709) (925)
Financing activities:    
Proceeds from issuance of common stock and warrants pursuant to public and private offerings 8,636,946
Stock issuance costs associated with public and private offerings   (251,891)
Proceeds from issuance of common stock pursuant to FBR At-the-Market Sales Agreement 4,142,456
Costs associated with issuance of common stock (132,080)
Proceeds from issuance of common stock pursuant to the equity line 38,400
Proceeds from the exercises of stock options 1,882
Principal repayment - financing lease (6,803)
Net cash provided by financing activities 4,005,455 8,423,455
Effect of exchange rate on cash and cash equivalents (34,188) (3,669)
Net (decrease) increase in cash and cash equivalents (3,563,009) 1,174,230
Cash and cash equivalents at beginning of year 8,983,717 7,809,487
Cash and cash equivalents at end of year 5,420,708 8,983,717
Supplemental information:    
Cash paid for state income taxes 11,132 2,580
Cash paid for lease liabilities:    
Operating lease: 140,017
Financing lease: 8,544
Non-cash investing and financing activities:    
Right-of use assets and lease liabilities recognized on January 1, 2019 255,965
Deferred issuance cost reclassified to additional-paid-in capital 33,535
Issuance of restricted common stock to vendor for website development costs 46,500
Issuance of common stock to vendor included in prepaid expenses $ 2,550