Income Taxes (Details 2)	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018
Income Tax Disclosure [Abstract]
Federal tax at statutory rate	(21.00%)	(21.00%)
State tax benefits, plus sale of NJ NOL, net of federal benefit	(8.80%)	(12.50%)
Foreign tax rate difference	0.30%	0.20%
Orphan drug and research and development credits	1.80%	1.10%
Permanent differences	2.10%	0.90%
Foreign NOL adjustments	2.50%
Expiration of tax attributes	8.80%	8.40%
Change in valuation allowance	8.30%	22.90%
Income tax benefit	(6.00%)