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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2019
Income Tax Disclosure [Abstract]  
Schedule of income tax benefit
   2019   2018 
Federal  $-   $- 
Foreign   -    - 
State   (610,676)   - 
Income tax benefit  $(610,676)  $- 
Schedule of deferred tax assets and liabilities
   2019   2018 
Net operating loss carry forwards  $23,936,000   $22,996,000 
Orphan drug and research and development credit carry forwards   8,315,000    8,333,000 
Equity based compensation   1,331,000    1,331,000 
Intangibles   1,051,000    1,164,000 
Total   34,633,000    33,824,000 
Valuation allowance   (34,633,000)   (33,824,000)
Net deferred tax assets  $-   $- 
Schedule of federal and state statutory tax rates and the provision for income tax benefit

    2019     2018  
Federal tax at statutory rate     (21.0 )%     (21.0 )%
State tax benefits, plus sale of NJ NOL, net of federal benefit     (8.8 )     (12.5 )
Foreign tax rate difference     0.3       0.2  
Orphan drug and research and development credits     1.8       1.1  
Permanent differences     2.1       0.9  
Foreign NOL adjustments     2.5       -  
Expiration of tax attributes     8.8       8.4  
Change in valuation allowance     8.3       22.9  
Income tax benefit     (6.0 )%          - %