Consolidated Statement of Changes in Shareholders' Equity (Unaudited) - USD ($)	Common Stock	Additional Paid-In Capital	Accumulated Other Comprehensive Loss	Accumulated Deficit	Total
Balance at Dec. 31, 2017	$ 8,731	$ 163,581,026		$ (157,270,045)	$ 6,319,712
Balance, Shares at Dec. 31, 2017	8,730,640
Issuance of common stock pursuant to Lincoln Park Equity Line	$ 20	38,380			38,400
Issuance of common stock pursuant to Lincoln Park Equity Line, shares	20,161
Share-based compensation expense		198,395			198,395
Net loss				(3,933,548)	(3,933,548)
Balance at Jun. 30, 2018	$ 8,751	163,817,801		(161,203,593)	2,622,959
Balance, Shares at Jun. 30, 2018	8,750,801
Balance at Mar. 31, 2018	$ 8,741	163,708,786		(159,647,251)	4,070,276
Balance, Shares at Mar. 31, 2018	8,740,723
Issuance of common stock pursuant to Lincoln Park Equity Line	$ 10	18,590			18,600
Issuance of common stock pursuant to Lincoln Park Equity Line, shares	10,078
Share-based compensation expense		90,425			90,425
Net loss				(1,556,342)	(1,556,342)
Balance at Jun. 30, 2018	$ 8,751	163,817,801		(161,203,593)	2,622,959
Balance, Shares at Jun. 30, 2018	8,750,801
Balance at Dec. 31, 2018	$ 17,683	172,436,176	$ (3,669)	(166,170,020)	6,280,170
Balance, Shares at Dec. 31, 2018	17,682,839
Balance at Mar. 31, 2019	$ 18,189	173,076,044	(3,020)	(167,809,647)	5,281,566
Balance, Shares at Mar. 31, 2019	18,189,208
Balance at Dec. 31, 2018	$ 17,683	172,436,176	(3,669)	(166,170,020)	6,280,170
Balance, Shares at Dec. 31, 2018	17,682,839
Issuance of common stock pursuant to FBR At Market Sales Issuance Agreement	$ 861	841,383			842,244
Issuance of common stock pursuant to FBR At Market Sales Issuance Agreement, shares	861,352
Issuance costs associated with FBR At Market Sales Issuance Agreement		(33,215)			(33,215)
Issuance of common stock to vendor	$ 197	160,860			161,057
Issuance of common stock to vendor, shares	197,019
Share-based compensation expense		152,465			152,465
Foreign currency translation adjustment			(3,339)		(3,339)
Net loss				(3,763,148)	(3,763,148)
Balance at Jun. 30, 2019	$ 18,741	173,557,669	(7,008)	(169,933,168)	3,636,234
Balance, Shares at Jun. 30, 2019	18,741,210
Balance at Mar. 31, 2019	$ 18,189	173,076,044	(3,020)	(167,809,647)	5,281,566
Balance, Shares at Mar. 31, 2019	18,189,208
Issuance of common stock pursuant to FBR At Market Sales Issuance Agreement	$ 415	319,245			319,660
Issuance of common stock pursuant to FBR At Market Sales Issuance Agreement, shares	414,983
Issuance costs associated with FBR At Market Sales Issuance Agreement		(13,832)			(13,832)
Issuance of common stock to vendor	$ 137	103,320			103,457
Issuance of common stock to vendor, shares	137,019
Share-based compensation expense		72,892			72,892
Foreign currency translation adjustment			(3,988)		(3,988)
Net loss				(2,123,521)	(2,123,521)
Balance at Jun. 30, 2019	$ 18,741	$ 173,557,669	$ (7,008)	$ (169,933,168)	$ 3,636,234
Balance, Shares at Jun. 30, 2019	18,741,210