Consolidated Statement of Changes in Shareholders' Equity (Unaudited) - 6 months ended Jun. 30, 2018 - USD ($)	Total	Common Stock	Additional Paid-In Capital	Accumulated Deficit
Beginning Balance at Dec. 31, 2017	$ 6,319,712	$ 8,731	$ 163,581,026	$ (157,270,045)
Beginning Balance, Shares at Dec. 31, 2017		8,730,640
Issuance of common stock pursuant to Lincoln Park Equity Line	38,400	$ 20	38,380
Issuance of common stock pursuant to Lincoln Park Equity Line, Shares		20,161
Share-based compensation expense	198,395		198,395
Net loss	(3,933,548)			(3,933,548)
Ending Balance at Jun. 30, 2018	$ 2,622,959	$ 8,751	$ 163,817,801	$ (161,203,593)
Ending Balance, Shares at Jun. 30, 2018		8,750,801