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Stock Option Plans and Warrants to Purchase Common Stock (Details Textual) - USD ($)
12 Months Ended
Nov. 03, 2017
Dec. 16, 2016
Nov. 09, 2016
Dec. 31, 2017
Dec. 31, 2016
Mar. 31, 2018
Stock Option Plans and Warrants to Purchase Common Stock (Textual)            
Warrants outstanding       261,250    
Warrants to purchase of common stock 51,151          
Common stock, value, issued       $ 8,731 $ 5,470 $ 8,741
Weighted average grant fair value       $ 1.54 $ 3.90  
Warrant liability         $ (892,860)  
Exercisable, weighted average remaining contractual term       8 years 2 months 5 days    
Common stock shares issued     303,694      
Warrants exercise price $ 2.50          
Compensation cost for stock options not yet recognized       $ 512,766    
Warrant [Member]            
Stock Option Plans and Warrants to Purchase Common Stock (Textual)            
Warrants to purchase of common stock 1,575,500 2,087,500 42,444 33,400    
Share price $ 2.00 $ 3.95        
Common stock, value, issued   $ 3.16        
Underwriters partially exercised over allotment   $ 282,505        
Warrant liability       $ 892,860    
Common stock shares issued 982,000 1,670,000 33,978      
Warrants exercise price $ 2.00     $ 3.95    
Warrants, description       Underlying the warrant for a four-year period commencing one year from the effective date of the offering.    
Stock options [Member]            
Stock Option Plans and Warrants to Purchase Common Stock (Textual)            
Exercisable options       439,963    
Weighted average grant fair value       $ 2.24 $ 5.30  
Options granted       476,100 66,875  
Weighted average exercise price       $ 10.77    
Exercisable, weighted average remaining contractual term       7 years 22 days    
Options outstanding, shares       785,655    
2015 Equity Incentive Plan [Member]            
Stock Option Plans and Warrants to Purchase Common Stock (Textual)            
Number of options available under Equity Incentive Plan       600,000