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Shareholders' Equity (Details) - USD ($)
1 Months Ended 2 Months Ended 3 Months Ended 12 Months Ended
Nov. 03, 2017
Aug. 11, 2017
May 24, 2017
May 04, 2017
Jan. 03, 2017
Dec. 16, 2016
Nov. 09, 2016
Sep. 09, 2016
Feb. 21, 2018
Jul. 31, 2017
Nov. 30, 2016
Aug. 29, 2016
May 31, 2016
Mar. 31, 2016
Nov. 30, 2013
Oct. 25, 2017
Mar. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Shareholders' Equity (Textual)                                      
Preferred stock, shares authorized                                 350,000 350,000 350,000
Preferred stock, shares issued                                
Preferred stock, shares outstanding                                
Value of shares issued to Lincoln Park                                 $ 19,800 $ 115,930 $ 1,712,320
Value of shares issued to FBR                                   $ 1,015,265  
Common stock issued on cashless basis             303,694                        
Common stock, shares issued                                 8,740,723 8,730,640 5,470,032
Warrants [Member]                                      
Shareholders' Equity (Textual)                                      
At market issuance sales agreement aggregate gross proceeds $ 5,115,000                                    
Common stock, shares issued                     33,978                
Issuance of common stock from exercise of stock options, shares                     42,444                
Warrent exercise price $ 2.50                                    
Direct offering [Member]                                      
Shareholders' Equity (Textual)                                      
Common stock, shares issued 982,000                                    
Purchase price, per share $ 2.00                                    
Lincoln Park [Member]                                      
Shareholders' Equity (Textual)                                      
Regular purchase shares maximum amount per agreement                           10,000          
Maximum amount of regular purchase per agreement                           $ 750,000          
Maximum additional commitment shares upon relative proportion of purchases in a regular purchase                           50,000          
Maximum (possible) value of agreement                           $ 12,000,000          
Common stock purchase agreement with Lincoln Park, description                           The Company entered into a common stock purchase agreement with Lincoln Park. The 2016 Lincoln Park equity facility allows the Company to require Lincoln Park to purchase up to 10,000 shares ("Regular Purchase") of the Company's common stock every two business days, up to an aggregate of $12.0 million over approximately a 36-month period with such amounts increasing as the quoted stock price increases. The Regular Purchase may be increased up to 15,000 shares of common stock if the closing price of the common shares is not below $10.00, up to 20,000 shares of common stock if the closing price of the common shares is not below $15.00 and up to 25,000 shares of common stock if the closing price of the common shares is not below $20.00. The purchase price for the Regular Purchase shall be equal to the lesser of (i) the lowest sale price of the common shares during the purchase date, or (ii) the average of the three lowest closing sale prices of the common shares during the twelve business days prior to the purchase date. Each Regular Purchase shall not exceed $750,000. Furthermore, for each purchase by Lincoln Park, additional commitment shares in commensurate amounts up to a total of 50,000 shares will be issued based upon the relative proportion of the aggregate amount of $12.0 million. In addition to the Regular Purchase and provided that the closing price of the common shares is not below $7.50 on the purchase date, the Company in its sole discretion may direct Lincoln Park on each purchase date to purchase on the next stock trading day ("Accelerated Purchase Date") additional shares of Company stock up to the lesser of (i) three times the number of shares purchased following a Regular Purchase or (ii) 30% of the trading volume of shares traded on the Accelerated Purchase Date at a price equal to the lesser of the closing sale price on the Accelerated Purchase Date or 95% of the Accelerated Purchase Date's volume weighted average price.          
Available from an equity line                                 $ 10,200,000 $ 10,200,000  
Value of shares granted                           $ 81,000          
FBR [Member]                                      
Shareholders' Equity (Textual)                                      
Common stock purchase agreement with FRB, description   The Sales Agreement provided that FBR was entitled to compensation for its services in an amount equal to 3% of the gross proceeds from the sale of shares sold under the Sales Agreement. The offering costs incurred to register the shares pursuant to the Sales Agreement were $164,825.                                  
Common stock with aggregate gross proceeds   $ 4,800,000                                  
Common Stock [Member]                                      
Shareholders' Equity (Textual)                                      
Value of shares issued to Lincoln Park                                 $ 10 50 $ 277
Value of shares issued to FBR                                   $ 450  
Issuance of common stock to vendor, shares         2,500       10,083     2,500 5,000         2,500 7,500
Fair value of fully vested shares, per share         $ 2.37                            
Warrants issued to purchase shares       250,000                              
Common stock issued on cashless basis       200,125                             352,942
Issuance of common stock pursuant to Lincoln Park Equity Line, Shares                                 10,083 50,483 277,135
Issuance of common stock pursuant to FBR At-the-Market Sales Agreement, Shares                                   450,000  
Common stock, shares issued 1,575,500                                    
Purchase price, per share $ 2.00                                    
Value of shares granted                                   $ 1,125 $ 47,244
Number of common stock shares sold                                   50,000 260,000
Number of commitment shares issued                                   483 7,135
Net proceeds from common stock sold                                   $ 115,930 $ 1,712,320
Common Stock [Member] | Warrants [Member]                                      
Shareholders' Equity (Textual)                                      
Warrants issued to purchase shares 51,151         2,087,500                          
Common stock, shares issued           1,670,000                          
Purchase price, per share           $ 3.16                          
Underwriters partially exercised over allotment           $ 282,505                          
Warrent exercise price $ 2.50         $ 3.95                          
Common Stock [Member] | Private placement [Member]                                      
Shareholders' Equity (Textual)                                      
Common stock, shares issued 982,000                                    
Purchase price, per share $ 2.00                                    
Common Stock [Member] | Lincoln Park [Member]                                      
Shareholders' Equity (Textual)                                      
Common stock purchase agreement with Lincoln Park, description                             The Company entered into a common stock purchase agreement with Lincoln Park Capital Fund, LLC ("Lincoln Park"). The Lincoln Park equity facility allowed the Company to require Lincoln Park to purchase up to $10.6 million of our common stock over a 36-month period depending on certain conditions.        
Issuance of common stock pursuant to Lincoln Park Equity Line, Shares     10,096             40,387                  
Common stock, shares issued                                     277,135
Common Stock [Member] | FBR [Member]                                      
Shareholders' Equity (Textual)                                      
Issuance of common stock pursuant to FBR At-the-Market Sales Agreement, Shares                               450,000      
Common stock, shares issued 1,575,500                                    
Purchase price, per share $ 2.00                                    
Common Stock [Member] | FBR [Member] | Private placement [Member]                                      
Shareholders' Equity (Textual)                                      
Common stock, shares issued 982,000                                    
Purchase price, per share $ 2.00                                    
Common Stock [Member] | SciClone [Member]                                      
Shareholders' Equity (Textual)                                      
Common stock, shares issued               352,942                      
Common stock purchase agreement price               $ 3,000,000                      
Additional Paid-In Capital                                      
Shareholders' Equity (Textual)                                      
Value of shares issued to Lincoln Park                                 $ 19,790 115,880 $ 1,712,043
Value of shares issued to FBR                                   $ 1,014,815