Consolidated Statement of Changes in Shareholders' Equity (Unaudited) - 6 months ended Jun. 30, 2017 - USD ($)	Total	Common Stock	Additional Paid-In Capital	Accumulated Deficit
Beginning Balance at Dec. 31, 2016	$ 7,397,248	$ 5,470	$ 157,514,740	$ (150,122,962)
Beginning Balance, Shares at Dec. 31, 2016		5,470,032
Issuance of common stock pursuant to Lincoln Park Equity Line	23,100	$ 10	23,090
Issuance of common stock pursuant to Lincoln Park Equity Line, Shares		10,096
Issuance of common stock from cashless exercise of warrants		$ 200	(200)
Issuance of common stock from cashless exercise of warrants, Shares		200,125
Issuance of common stock to vendors	5,925	$ 3	5,922
Issuance of common stock to vendors, Shares		2,500
Share-based compensation expense	240,674		240,674
Net loss	(4,045,035)			(4,045,035)
Ending Balance at Jun. 30, 2017	$ 3,621,912	$ 5,683	$ 157,784,226	$ (154,167,997)
Ending Balance, Shares at Jun. 30, 2017		5,682,753