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Summary of Significant Accounting Policies (Details Textual)
6 Months Ended
Jun. 30, 2017
Segment
$ / shares
Jun. 30, 2016
$ / shares
Summary of Significant Accounting Policies (Textual)    
Number of operating segments | Segment 2  
Minimum [Member]    
Summary of Significant Accounting Policies (Textual)    
Intangible assets, estimated useful life 11 years  
Maximum [Member]    
Summary of Significant Accounting Policies (Textual)    
Intangible assets, estimated useful life 16 years  
Directors Upon Re-election [Member]    
Summary of Significant Accounting Policies (Textual)    
Stock option, expiration period 1 year  
Permanent Employees Or Director [Member]    
Summary of Significant Accounting Policies (Textual)    
Stock option, expiration period 10 years  
Terminated Employees Or Directors [Member]    
Summary of Significant Accounting Policies (Textual)    
Stock option, expiration period 3 months  
Stock Option [Member]    
Summary of Significant Accounting Policies (Textual)    
Weighted average exercise price, outstanding $ 11.34 $ 19.65
Dividend yield 0.00% 0.00%
Expected term 4 years 4 years
Forfeiture rate 12.00% 12.00%
Stock option vesting, description
Stock options issued to employees generally vest 25% on the grant date, then 25% each subsequent year for a period of three years.
 
Weighted average exercise price, granted $ 2.55 $ 7.70
Stock Option [Member] | Minimum [Member]    
Summary of Significant Accounting Policies (Textual)    
Volatility rate 90.00% 116.00%
Risk free interest rate 1.60% 0.96%
Stock Option [Member] | Maximum [Member]    
Summary of Significant Accounting Policies (Textual)    
Volatility rate 93.00% 121.00%
Risk free interest rate 1.81% 1.52%
Warrant [Member]    
Summary of Significant Accounting Policies (Textual)    
Weighted average exercise price, outstanding $ 4.45 $ 7.38