Nature of Business (Details)	3 Months Ended		12 Months Ended
	Mar. 31, 2017 USD ($) Segment	Mar. 31, 2016 USD ($)	Dec. 31, 2016 USD ($)	Dec. 31, 2015 USD ($)
Nature of Business (Textual)
Number of operating segments | Segment	2
Cash and cash equivalents	$ 7,143,821	$ 4,260,440	$ 8,772,567	$ 4,921,545
Net decrease in cash and cash equivalents	$ (1,628,746)	(661,105)
Percentage decrease in cash and cash equivalents	19.00%
Cash used in operations	$ (1,626,615)	(637,839)
Working capital	5,681,951		7,243,918
Decrease in working capital	$ 1,561,967
Percentage of decrease in working capital	22.00%
Active grant funding available	$ 15,800,000
Proceeds from the sale of NJ NOL			530,143
Equity facility, available amount	$ 10,300,000
Equity facility expiration date	Mar. 31, 2019
Accumulated deficit	$ (151,856,399)		$ (150,122,962)
Net loss	$ (1,733,437)	$ (1,149,433)