Income Taxes (Tables)

12 Months Ended

Dec. 31, 2015

Income Taxes [Abstract]

Schedule of income tax benefit

	2015			2014
Federal	$	-		$	-
State		(488,933	)		(616,872	)
Income tax benefit	$	(488,933	)	$	(616,872	)

Schedule of deferred tax asset

	2015			2014
Net operating loss carry forwards	$	31,216,000		$	29,594,000
Orphan drug and research and development credit carry forwards		4,909,000			3,556,000
Equity based compensation		1,923,000			2,049,000
Intangibles		2,090,000			2,140,000
Total		40,138,000			37,339,000
Valuation allowance		(40,138,000	)		(37,339,000	)
Net deferred tax assets	$	-		$	-

Schedule of reconciliation of income tax rate

	2015			2014
Income tax loss at federal statutory rate		(34.00	)%		(34.00	)%
State tax benefits, plus sale of NJ NOLs, net of federal benefit		(6.00	)		(6.00	)
Subtotal		(40.00	)		(40.00	)
Valuation allowance		34.12			31.58
Income tax benefit		(5.88	)%		(8.42	)%