XML 54 R43.htm IDEA: XBRL DOCUMENT v3.3.1.900
Shareholders' Deficiency (Details) - USD ($)
1 Months Ended 12 Months Ended
Nov. 30, 2015
Oct. 31, 2015
Sep. 30, 2015
Jul. 31, 2015
Jul. 29, 2015
Jun. 30, 2015
May. 31, 2015
Apr. 30, 2015
Mar. 31, 2015
Feb. 28, 2015
Sep. 30, 2014
Aug. 31, 2014
Jul. 31, 2014
May. 31, 2014
Apr. 30, 2014
Mar. 31, 2014
Jan. 31, 2014
Nov. 30, 2013
Dec. 31, 2015
Dec. 31, 2014
Shareholders' Equity (Textual)                                        
Preferred stock, shares authorized                                     350,000 350,000
Preferred stock, shares issued                                    
Preferred stock, shares outstanding                                    
Common stock purchase agreement         $ 10,000,000                              
Weighted average price of common stock percentage         80.00%                              
Maximum investment amount on shares         $ 3,000,000                              
Investment ownership percentage         9.99%                              
Maturity date         Apr. 15, 2016                              
Promissory note principal amount, percentage         3.00%                              
Equity Line Purchase         $ 500,000                           $ 2,500,000  
Issuance cost         $ (453,162)                              
Commitment fee         3.00%                              
Research and Development in Process                                     $ 4,000,000
Net proceeds received from public offering                                       1,937,894
Value of shares issued                                     $ 1,339,177 $ 470,475
Warrant [Member]                                        
Shareholders' Equity (Textual)                                        
Issuance of common stock from exercise of stock options, shares                                     1,746,429 586,081
Stock Issued During Period, Shares, Conversion of Units                                       1,169,318
Kodiak Capital [Member]                                        
Shareholders' Equity (Textual)                                        
Common stock right to sell in future period         $ 5,000,000                              
Kingsbrook [Member]                                        
Shareholders' Equity (Textual)                                        
Common stock right to sell in future period         4,000,000                              
River North [Member]                                        
Shareholders' Equity (Textual)                                        
Common stock purchase agreement         10,000,000                              
Common stock right to sell in future period         $ 1,000,000                              
Lincoln Park Capital Fund Llc [Member]                                        
Shareholders' Equity (Textual)                                        
Value of shares issued                                   $ 10,600,000    
Closing price of common shares                                   $ 2.50    
Period For Aff Iliates To Purchase Common Stock Under Agreement                                   In November 2013, the Company entered into a common stock purchase agreement with Lincoln Park Capital Fund, LLC ("Lincoln Park"). The Lincoln Park equity facility allows the Company to require Lincoln Park to purchase up to 75,000 shares ("Regular Purchase") of the Company's common stock every two business days, up to an aggregate of $10.6 million over approximately a 36-month period depending on certain conditions, including the quoted market price of the Company's common stock on such date.    
Number of shares issued as commitment fee                                   100,000    
Maximum Additional Commitment Shares Upon Relative Proportion Of Purchases Compared                                   122,070    
Proceed from common stock agreement gross                                   $ 10,000,000    
Description Of Purchase Agreement                                   In addition to the Regular Purchase and provided that the closing price of the common shares is not below $1.50 on the purchase date, the Company in its sole discretion may direct Lincoln Park on each purchase date to purchase on the next stock trading day ("Accelerate Purchase Date") additional shares of Company stock up to the lesser of (i) two times the number of shares purchased following a Regular Purchase or (ii) 30% of the trading volume of shares traded on the Accelerated Purchase Date as a price equal to the lesser of the closing sale price on the Accelerated Purchase Date or 95% of the Accelerated Purchase Date's volume weighted average price.    
Common Stock [Member]                                        
Shareholders' Equity (Textual)                                        
Issuance of common stock from exercise of warrants, shares                                     1,746,429  
Issuance of common stock pursuant to Lincoln Park Equity line, Shares 75,894 151,843       384,237 76,364   153,010       76,904   76,907 76,932     841,348 230,743
Issuance of common stock as partial consideration for services performed, Shares                                     166,282 121,000
Issuance of common stock from exercise of stock options, shares                       336,081             33,125 36,672
Issuance of common stock pursuant to Equity Line Purchase Agreement, Shares     609,535                               4,545,770  
Equity Line Purchase                                     $ 4,546  
Issuance cost                                      
Issuance of common stock from cashless exercise of warrants,shares     25,000         8,125       65,115               143,004
Stock Issued During Period Share Of Vested Stock Options Exercised                         7,500 29,172            
Issuance of common stock to collaboration partner, Shares                           43,067           43,067
Research and Development in Process                     $ 1,849,113                  
Stock Issued During Period, Shares, Conversion of Units                                       1,886,530
Value of shares issued                                     $ 842 $ 231
Number of common stock shares sold                                     825,000 225,000
Number of commitment shares issued                                     16,348 5,743
Net proceeds from common stock sold                                     $ 1,339,177 $ 470,475
Common Stock [Member] | Warrant [Member]                                        
Shareholders' Equity (Textual)                                        
Issuance of common stock from exercise of stock options, shares                                 250,000      
Issuance of common stock from cashless exercise of warrants,shares       7,143 198,714     356,786 482,000 701,786             77,889