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Consolidated Statements of Cash Flows (Unaudited) - USD ($)
6 Months Ended 12 Months Ended
Jun. 30, 2015
Jun. 30, 2014
Dec. 31, 2014
Dec. 31, 2013
Operating activities:        
Net loss $ (8,547,016) $ (4,280,225) $ (6,706,972) $ (10,058,996)
Adjustments to reconcile net loss to net cash used in operating activities:        
Amortization and depreciation $ 121,657 122,494 245,787 230,071
Charge for common stock issued for collaboration agreement     100,002 1,500,000
Common stock issued in exchange for services     256,040 $ 82,148
Issuance of common stock for acquisition of in-process research and development     4,000,000  
Warrants issued to vendors   4,775 4,775 $ 4,775
Issuance of common stock $ 118,761 253,542    
Change in fair value of warrant liability 4,955,110 995,098 (3,436,195) 3,654,770
Share-based compensation 279,188 297,919 720,150 803,060
Change in operating assets and liabilities:        
Contracts and grants receivable $ 61,202 402,026 72,319 (527,778)
Taxes receivable   750,356 750,356 (750,356)
Prepaid expenses $ (70,610) 71,924 (37,537) 5,302
Accounts payable (367,098) 445,309 1,483,255 395,787
Accrued compensation (266,943) (163,415) 81,291 204,244
Total adjustments 4,831,267 3,180,028 4,240,243 5,602,023
Net cash used in operating activities (3,715,749) (1,100,197) (2,466,729) $ (4,456,973)
Investing activities:        
Payments for acquisition of in-process research and development     (250,000)  
Purchases of office equipment     (50,866) $ (17,728)
Purchases of fixed assets (13,706) (42,191)    
Net cash used in investing activities (13,706) (42,191) (300,866) (17,728)
Financing activities:        
Net proceeds from sale of units containing common stock and warrants     1,937,894 6,210,537
Proceeds from issuance of common stock pursuant to the equity line 1,115,025 $ 314,475 470,475 528,051
Proceeds from exercise of warrants 1,113,164      
Proceeds from exercise of stock options 11,750 $ 13,003 28,078 235,975
Net cash provided by financing activities 2,239,939 327,478 2,436,447 6,974,563
Net decrease in cash and cash equivalents (1,489,516) (814,910) (331,148) 2,499,862
Cash and cash equivalents at beginning of period 5,525,094 5,856,242 5,856,242 3,356,380
Cash and cash equivalents at end of period 4,035,578 5,041,332 $ 5,525,094 5,856,242
Supplemental disclosure of non cash investing and financing activities:        
Fair Value of warrants issued in Unit Offering       4,827,788
Reclassification of warrant liability to additional paid in capital upon partial exercise of warrants issued in unit offering $ 2,543,117 $ 502,025 $ 1,055,490 201,311
Supplemental information:        
Cash paid for state income taxes     $ 6,994 $ 3,080