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Consolidated Statements of Changes in Shareholders' Equity Deficiency (Unaudited) - USD ($)
Total
Common Stock
Additional paid-in capital
Accumulated deficit
Beginning Balance at Dec. 31, 2012 $ 3,551,106 $ 11,169 $ 125,820,318 $ (122,280,381)
Beginning Balance, Shares at Dec. 31, 2012   11,168,905    
Common stock issued in Unit offering 6,210,537 $ 6,774 6,203,763  
Common stock issued in unit offering, shares   6,773,995    
Warrants issued in Unit offering (4,827,788)   (4,827,788)  
Issuance of common stock to collaboration partner 1,500,000 $ 1,034 1,498,966  
Issuance of common stock to collaboration partner, Shares   1,034,483    
Fair value of common stock warrants issued to vendors 4,775   4,775  
Issuance of common stock pursuant to Lincoln Park equity line 528,051 $ 383 527,668  
Issuance of common stock pursuant to lincoln park equity line, shares   383,370    
Issuance of common stock to vendor 82,148 $ 55 82,093  
Issuance of common stock to vendor, Shares   55,104    
Reclassification of warrant liability to additional paid in capital upon partial exercise of warrants issued in unit offering 201,311   201,311  
Issuance of shares from exercise of stock options and warrants 235,975 $ 211 235,764  
Issuance of shares from exercise of stock options and warrants, Shares   210,582    
Stock-based compensation expense 803,060   $ 803,060  
Net loss (10,058,996)     $ (10,058,996)
Balance at Dec. 31, 2013 (1,769,821) $ 19,626 $ 130,549,930 $ (132,339,377)
Balance, Shares at Dec. 31, 2013   19,626,439    
Common stock issued in Unit offering 1,937,894 $ 1,887 1,936,007  
Common stock issued in unit offering, shares   1,886,530    
Issuance of common stock to collaboration partner $ 100,002 $ 43 99,959  
Issuance of common stock to collaboration partner, Shares   43,067    
Issuance of common stock from cashless exercise of warrants   $ 143 (143)  
Issuance of common stock from cashless exercise of warrants,shares   143,004    
Shares issued in connection with acquisition of in-process research and development $ 3,750,000 $ 1,849 3,748,151  
Shares issued in connection with acquisition of in-process research and development,shares   $ 1,849,113    
Fair value of common stock warrants issued to vendors 4,775   4,775  
Issuance of common stock pursuant to Lincoln Park equity line 470,475 $ 231 470,244  
Issuance of common stock pursuant to lincoln park equity line, shares   230,743    
Issuance of common stock to vendor 256,040 $ 121 255,919  
Issuance of common stock to vendor, Shares   121,000    
Reclassification of warrant liability to additional paid in capital upon partial exercise of warrants issued in unit offering 1,055,490   1,055,490  
Issuance of shares from exercise of stock options 28,078 $ 37 28,041  
Issuance of shares from exercise of stock options,shares   36,672    
Stock-based compensation expense 720,150   $ 720,150  
Net loss (6,706,972)     $ (6,706,972)
Balance at Dec. 31, 2014 (153,889) $ 23,937 $ 138,868,523 $ (139,046,349)
Balance, Shares at Dec. 31, 2014   23,936,568    
Issuance of common stock pursuant to Lincoln Park equity line 1,115,025 $ 614 1,114,411  
Issuance of common stock pursuant to lincoln park equity line, shares   613,611    
Issuance of common stock to vendor 118,761 $ 77 118,684  
Issuance of common stock to vendor, Shares   77,243    
Reclassification of warrant liability to additional paid in capital upon partial exercise of warrants issued in unit offering 2,543,117   2,543,117  
Issuance of shares from exercise of stock options and warrants 1,113,164 $ 1,739 1,111,425  
Issuance of shares from exercise of stock options and warrants, Shares   1,739,286    
Issuance of shares from exercise of stock options 11,750 $ 8 11,742  
Issuance of shares from exercise of stock options,shares   8,125    
Stock-based compensation expense 279,188   $ 279,188  
Net loss (8,547,016)     $ (8,547,016)
Balance at Jun. 30, 2015 $ (3,519,900) $ 26,375 $ 144,047,090 $ (147,593,365)
Balance, Shares at Jun. 30, 2015   26,374,833