Consolidated Statements of Cash Flows (Unaudited) (USD $)	3 Months Ended
Mar. 31, 2015	Mar. 31, 2014
Operating activities:
Net loss	$ (4,569,322)us-gaap_NetIncomeLoss	$ (3,331,708)us-gaap_NetIncomeLoss
Adjustments to reconcile net loss to net cash used in operating activities:
Amortization and depreciation	59,926	62,087
Common stock issued to vendors	101,360sngx_IssuanceOfCommonStockValue	153,540sngx_IssuanceOfCommonStockValue
Warrants issued to vendors		4,775sngx_WarrantsIssuedToVendors
Share-based compensation	142,025us-gaap_ShareBasedCompensation	176,662us-gaap_ShareBasedCompensation
Change in fair value of warrant liability	3,011,616us-gaap_FairValueAdjustmentOfWarrants	1,742,090us-gaap_FairValueAdjustmentOfWarrants
Change in operating assets and liabilities:
Grants receivable	449,347	172,740
Taxes receivable		750,356
Prepaid expenses	41,382	37,771
Accounts payable	(459,603)	32,338
Accrued compensation	(282,841)	(188,430)
Total adjustments	3,063,212	2,943,929
Net cash used in operating activities	(1,506,110)	(387,779)
Investing activities
Purchases of fixed assets	(11,553)	(19,863)
Net cash used in investing activities	(11,553)	(19,863)
Financing Activities:
Net proceeds from issuance of common stock pursuant to the equity line	246,525	158,250
Proceeds from exercises of warrants	758,649us-gaap_ProceedsFromWarrantExercises
Net cash provided by financing activities	1,005,174	158,250
Net decrease in cash and cash equivalents	(512,489)	(249,392)
Cash and cash equivalents at beginning of period	5,525,094	5,856,242
Cash and cash equivalents at end of period	5,012,605	5,606,850
Supplemental disclosure of non cash investing and financing activities:
Reclassification of warrant liability to additional paid in capital upon partial exercises of warrants issued in unit offering	$ 1,648,811	$ 502,025

Carrying amount of a reclassification of warrant liability upon partial exercise of warrants issued in unit offering.

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