Income Taxes (Details 1) (USD $)	Dec. 31, 2014	Dec. 31, 2013
Summary of deferred tax assets
Net operating loss carry forwards	$ 29,594,000	$ 27,974,000
Orphan drug and research and development credit carry forwards	3,556,000	2,986,000
Equity based compensation	2,049,000	3,183,000
Intangibles	2,140,000	127,000
Total	37,339,000us-gaap_DeferredTaxAssetsGross	34,270,000us-gaap_DeferredTaxAssetsGross
Valuation allowance	(37,339,000)	(34,270,000)
Income tax benefits

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards.

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards.

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Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized.

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