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Consolidated Statements of Cash Flows (USD $)
 12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Operating activities:    
Net loss $ (6,706,972)us-gaap_NetIncomeLoss $ (10,058,996)us-gaap_NetIncomeLoss
Adjustments to reconcile net loss to net cash used in operating activities:    
Amortization and depreciation 245,787us-gaap_DepreciationDepletionAndAmortization 230,071us-gaap_DepreciationDepletionAndAmortization
Charge for common stock issued for collaboration agreement 100,002us-gaap_StockholdersEquityOther 1,500,000us-gaap_StockholdersEquityOther
Common stock issued in exchange for services 256,040us-gaap_IssuanceOfStockAndWarrantsForServicesOrClaims 82,148us-gaap_IssuanceOfStockAndWarrantsForServicesOrClaims
Issuance of common stock for acquisition of in-process research and development 4,000,000sngx_IssuancesOfCommonStockForAssetAcquisition   
Warrants issued to vendor 4,775sngx_WarrantsIssuedToVendor 4,775sngx_WarrantsIssuedToVendor
Stock-based compensation 720,150us-gaap_ShareBasedCompensation 803,060us-gaap_ShareBasedCompensation
Change in fair value of warrant liability (3,436,195)sngx_ChangeInFairValueOfWarrantLiability 3,654,770sngx_ChangeInFairValueOfWarrantLiability
Change in operating assets and liabilities:    
Grants and contracts receivable 72,319us-gaap_IncreaseDecreaseInAccountsAndOtherReceivables (527,778)us-gaap_IncreaseDecreaseInAccountsAndOtherReceivables
Taxes receivable 750,356us-gaap_IncreaseDecreaseInIncomeTaxesReceivable (750,356)us-gaap_IncreaseDecreaseInIncomeTaxesReceivable
Prepaid expenses (37,537)us-gaap_IncreaseDecreaseInPrepaidExpense 5,302us-gaap_IncreaseDecreaseInPrepaidExpense
Accounts payable 1,483,255us-gaap_IncreaseDecreaseInAccountsPayableTrade 395,787us-gaap_IncreaseDecreaseInAccountsPayableTrade
Accrued compensation 81,291us-gaap_IncreaseDecreaseInAccruedSalaries 204,244us-gaap_IncreaseDecreaseInAccruedSalaries
Total adjustments and change in operating assets and liabilities 4,240,243us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities 5,602,023us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities
Net cash used in operating activities (2,466,729)us-gaap_NetCashProvidedByUsedInOperatingActivities (4,456,973)us-gaap_NetCashProvidedByUsedInOperatingActivities
Investing activities:    
Payments for acquisition of in-process research and development (250,000)us-gaap_PaymentsToAcquireInProcessResearchAndDevelopment   
Purchases of office equipment (50,866)us-gaap_PaymentsToAcquireMachineryAndEquipment (17,728)us-gaap_PaymentsToAcquireMachineryAndEquipment
Net cash used in investing activities (300,866)us-gaap_NetCashProvidedByUsedInInvestingActivities (17,728)us-gaap_NetCashProvidedByUsedInInvestingActivities
Financing activities:    
Net proceeds from sale of units containing common stock and warrants 1,937,894us-gaap_ProceedsFromIssuanceOrSaleOfEquity 6,210,537us-gaap_ProceedsFromIssuanceOrSaleOfEquity
Net proceeds from issuance of common stock pursuant to the equity line 470,475us-gaap_ProceedsFromIssuanceOfCommonStock 528,051us-gaap_ProceedsFromIssuanceOfCommonStock
Proceeds from exercise of options and warrants 28,078us-gaap_ProceedsFromStockOptionsExercised 235,975us-gaap_ProceedsFromStockOptionsExercised
Net cash provided by financing activities 2,436,447us-gaap_NetCashProvidedByUsedInFinancingActivities 6,974,563us-gaap_NetCashProvidedByUsedInFinancingActivities
Net increase (decrease) in cash and cash equivalents (331,148)us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease 2,499,862us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease
Cash and cash equivalents at beginning of period 5,856,242us-gaap_CashAndCashEquivalentsAtCarryingValue 3,356,380us-gaap_CashAndCashEquivalentsAtCarryingValue
Cash and cash equivalents at end of period 5,525,094us-gaap_CashAndCashEquivalentsAtCarryingValue 5,856,242us-gaap_CashAndCashEquivalentsAtCarryingValue
Supplemental disclosure of non cash investing and financing activities:    
Fair Value of warrants issued in Unit Offering    4,827,788sngx_WarrantIssuedInUnitOffering
Reclassification of warrant liability upon partial exercise of warrants issued in unit offering 1,055,490sngx_AdditionalPaidInCapitalReclassificationOfWarrantLiability 201,311sngx_AdditionalPaidInCapitalReclassificationOfWarrantLiability
Supplemental information:    
Cash paid for state income taxes $ 6,994us-gaap_IncomeTaxesPaid $ 3,080us-gaap_IncomeTaxesPaid