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Consolidated Statements of Cash Flows (Unaudited) (USD $)
 9 Months Ended 12 Months Ended
Sep. 30, 2014
Sep. 30, 2013
Dec. 31, 2013
Dec. 31, 2012
Operating activities:        
Net loss $ (8,629,780)us-gaap_NetIncomeLoss $ (11,052,427)us-gaap_NetIncomeLoss $ (10,058,996)us-gaap_NetIncomeLoss $ (4,163,008)us-gaap_NetIncomeLoss
Adjustments to reconcile net loss to net cash used in operating activities:        
Amortization and depreciation 183,960us-gaap_DepreciationDepletionAndAmortization 171,666us-gaap_DepreciationDepletionAndAmortization 230,071us-gaap_DepreciationDepletionAndAmortization 230,630us-gaap_DepreciationDepletionAndAmortization
Common stock issued to employee        10,000sngx_IssuanceOfCommonStockToEmployees
Issuances of common stock for acquisition of in-process research and development 3,750,000sngx_IssuancesOfCommonStockForAssetAcquisition       
Charge for common stock issued for collaboration agreement     1,500,000us-gaap_StockholdersEquityOther   
Common stock issued in exchange for services     82,148us-gaap_IssuanceOfStockAndWarrantsForServicesOrClaims 21,000us-gaap_IssuanceOfStockAndWarrantsForServicesOrClaims
Warrants replaced in exchange for renegotiated agreement        429,902us-gaap_DebtConversionConvertedInstrumentAmount1
Warrants issued to vendor 4,775sngx_AdjustmentsToAdditionalPaidInCapitalWarrantIssuedToVendors 0sngx_AdjustmentsToAdditionalPaidInCapitalWarrantIssuedToVendors 4,775sngx_AdjustmentsToAdditionalPaidInCapitalWarrantIssuedToVendors   
Issuance of common stock 356,042sngx_IssuanceOfCommonStockValue 1,559,588sngx_IssuanceOfCommonStockValue    
Stock-based compensation 458,914us-gaap_ShareBasedCompensation 571,171us-gaap_ShareBasedCompensation 803,060us-gaap_ShareBasedCompensation 462,170us-gaap_ShareBasedCompensation
Change in fair value of warrant liability 203,703sngx_ChangeInFairValueOfWarrantLiability 5,349,422sngx_ChangeInFairValueOfWarrantLiability 3,654,770sngx_ChangeInFairValueOfWarrantLiability   
Change in operating assets and liabilities:        
Grants receivable (470,957)us-gaap_IncreaseDecreaseInAccountsAndOtherReceivables 177,473us-gaap_IncreaseDecreaseInAccountsAndOtherReceivables (527,778)us-gaap_IncreaseDecreaseInAccountsAndOtherReceivables 23,165us-gaap_IncreaseDecreaseInAccountsAndOtherReceivables
Taxes receivable 750,356us-gaap_IncreaseDecreaseInIncomeTaxesReceivable    (750,356)us-gaap_IncreaseDecreaseInIncomeTaxesReceivable 574,157us-gaap_IncreaseDecreaseInIncomeTaxesReceivable
Prepaid expenses (70,116)us-gaap_IncreaseDecreaseInPrepaidExpense (57,367)us-gaap_IncreaseDecreaseInPrepaidExpense 5,302us-gaap_IncreaseDecreaseInPrepaidExpense 55,069us-gaap_IncreaseDecreaseInPrepaidExpense
Accounts payable 1,539,036us-gaap_IncreaseDecreaseInAccountsPayableTrade 90,082us-gaap_IncreaseDecreaseInAccountsPayableTrade 395,787us-gaap_IncreaseDecreaseInAccountsPayableTrade (179,053)us-gaap_IncreaseDecreaseInAccountsPayableTrade
Accrued compensation (173,755)us-gaap_IncreaseDecreaseInAccruedSalaries 26,059us-gaap_IncreaseDecreaseInAccruedSalaries 204,244us-gaap_IncreaseDecreaseInAccruedSalaries (99,565)us-gaap_IncreaseDecreaseInAccruedSalaries
Total adjustments 6,531,958us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities 7,888,094us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities 5,602,023us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities 1,527,475us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities
Net cash used in operating activities (2,097,822)us-gaap_NetCashProvidedByUsedInOperatingActivities (3,164,333)us-gaap_NetCashProvidedByUsedInOperatingActivities (4,456,973)us-gaap_NetCashProvidedByUsedInOperatingActivities (2,635,533)us-gaap_NetCashProvidedByUsedInOperatingActivities
Investing activities:        
Purchases of office equipment (47,025)us-gaap_PaymentsToAcquireMachineryAndEquipment (10,539)us-gaap_PaymentsToAcquireMachineryAndEquipment (17,728)us-gaap_PaymentsToAcquireMachineryAndEquipment (4,755)us-gaap_PaymentsToAcquireMachineryAndEquipment
Net cash used in investing activities (47,025)us-gaap_NetCashProvidedByUsedInInvestingActivities (10,539)us-gaap_NetCashProvidedByUsedInInvestingActivities (17,728)us-gaap_NetCashProvidedByUsedInInvestingActivities (4,755)us-gaap_NetCashProvidedByUsedInInvestingActivities
Financing activities:        
Proceeds from sale of common stock, net    6,216,762us-gaap_StockIssuedDuringPeriodValueConversionOfUnits 6,210,537us-gaap_StockIssuedDuringPeriodValueConversionOfUnits   
Net proceeds from common stock pursuant to the equity line 470,475us-gaap_ProceedsFromIssuanceOfCommonStock    528,051us-gaap_ProceedsFromIssuanceOfCommonStock   
Proceeds from exercise of warrants and options 28,079us-gaap_ProceedsFromStockOptionsExercised 184,286us-gaap_ProceedsFromStockOptionsExercised 235,975us-gaap_ProceedsFromStockOptionsExercised   
Net cash provided by financing activities 498,554us-gaap_NetCashProvidedByUsedInFinancingActivities 6,401,048us-gaap_NetCashProvidedByUsedInFinancingActivities 6,974,563us-gaap_NetCashProvidedByUsedInFinancingActivities  
Net increase (decrease) in cash and cash equivalents (1,646,293)us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease 3,226,176us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease 2,499,862us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease (2,640,288)us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease
Cash and cash equivalents at beginning of period 5,856,242us-gaap_CashAndCashEquivalentsAtCarryingValue 3,356,380us-gaap_CashAndCashEquivalentsAtCarryingValue 3,356,380us-gaap_CashAndCashEquivalentsAtCarryingValue 5,996,668us-gaap_CashAndCashEquivalentsAtCarryingValue
Cash and cash equivalents at end of period 4,209,949us-gaap_CashAndCashEquivalentsAtCarryingValue 6,582,556us-gaap_CashAndCashEquivalentsAtCarryingValue 5,856,242us-gaap_CashAndCashEquivalentsAtCarryingValue 3,356,380us-gaap_CashAndCashEquivalentsAtCarryingValue
Supplemental disclosure of non cash investing and financing activities:        
Warrants issued in unit offering    4,827,788sngx_WarrantIssuedInUnitOffering 4,827,788sngx_WarrantIssuedInUnitOffering   
Reclassification of warrant liability to additional paid in capital relating to warrants exercised 1,055,490sngx_AdditionalPaidInCapitalReclassificationOfWarrantLiability 201,311sngx_AdditionalPaidInCapitalReclassificationOfWarrantLiability 201,311sngx_AdditionalPaidInCapitalReclassificationOfWarrantLiability   
Supplemental information:        
Cash paid for state income taxes     $ 3,080us-gaap_IncomeTaxesPaid $ 2,730us-gaap_IncomeTaxesPaid