Stock Option Plans and Warrants to Purchase Common Stock (Tables)

12 Months Ended

Dec. 31, 2013

Stock Options [Member]

Share-based Compensation Arrangement by Share-based Payment Award [Line Items]

Summary of option and warrant activity

	Options			Weighted Average Options Exercise Price
Balance at December 31, 2011		1,544,242		$	3.75
Granted		100,000			0.30
Exercised					-
Forfeited		(186,518	)		6.22
Balance at December 31, 2012		1,457,724		$	3.19
Granted		791,100			1.35
Exercised		(103,439	)		0.57
Forfeited		(93,874	)		2.84
Balance at December 31, 2013		2,051,511		$	2.63

Weighted-average range of exercise prices for options and warrants outstanding and exercisable

Price Range	Weighted Average Remaining Contractual Life in Years		Outstanding  Options		Exercisable  Options
$0.30-$2.20		8.2		1,299,302		842,305
$2.26-$4.10		8.0		229,459		184,638
$4.64-$8.60		4.9		426,500		426,500
$9.40-$11.60		3.2		93,750		93,750
$18.00-$25.60		0.1		2,500		2,500
Total		7.3		2,051,511		1,549,693

Warrant [Member]

Share-based Compensation Arrangement by Share-based Payment Award [Line Items]

Summary of option and warrant activity

	Warrants			Weighted  Average Warrant Exercise Price
Balance at December 31, 2011		2,701,569		$	4.40
Granted		774,873			0.56
Exercised		-			-
Expired/Cancelled		(633,104	)		5.40
Balance at December 31, 2012		2,843,338		$	3.13
Granted		5,421,581			1.65
Exercised		(107,143	)		1.65
Expired/Cancelled		(1,250	)		15.00
Balance at December 31, 2013		8,156,526		$	2.17

Weighted-average range of exercise prices for options and warrants outstanding and exercisable

Price Range	Weighted Average Remaining Contractual Life in Years		Outstanding  Warrants		Exercisable Warrants
$.53-$2.05		4.4		6,091,811		6,091,811
$2.80-$3.96		0.05		1,103,202		1,103,202
$5.50-$5.56		0.77		379,561		379,561
$5.60-$6.06		2.0		581,952		581,952
Total		3.44		8,156,526		8,156,526

Equity Incentive Plan [Member]

Share-based Compensation Arrangement by Share-based Payment Award [Line Items]

Summary of option and warrant activity

	December 31,
	2013			2012
Shares available for grant at beginning of year		129,711			60,692
Increase in shares available for the plan		1,250,000			-
Options granted		(791,100	)		(100,000	)
Options exercised		103,439			-
Options forfeited or expired		83,874			169,019
Shares available for grant at end of year		775,924			129,711