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Consolidated Statements of Cash Flows (Unaudited) (USD $)
9 Months Ended 12 Months Ended
Sep. 30, 2014
Sep. 30, 2013
Dec. 31, 2013
Dec. 31, 2012
Operating activities:        
Net loss $ (8,629,780) $ (11,052,427) $ (10,058,996) $ (4,163,008)
Adjustments to reconcile net loss to net cash used in operating activities:        
Amortization and depreciation 183,960 171,666 230,071 230,630
Common stock issued to employee        10,000
Issuances of common stock for acquisition of in-process research and development 4,000,000       
Charge for common stock issued for collaboration agreement     1,500,000   
Common stock issued in exchange for services     82,148 21,000
Warrants replaced in exchange for renegotiated agreement        429,902
Warrants issued to vendor 4,775 0 4,775   
Issuance of common stock 106,042 1,559,588    
Stock-based compensation 458,914 571,171 803,060 462,170
Change in fair value of warrant liability 203,703 5,349,422 3,654,770   
Change in operating assets and liabilities:        
Grants receivable (470,957) 177,473 (527,778) 23,165
Taxes receivable 750,356    (750,356) 574,157
Prepaid expenses (70,116) (57,367) 5,302 55,069
Accounts payable 1,539,036 90,082 395,787 (179,053)
Accrued compensation (173,755) 26,059 204,244 (99,565)
Total adjustments 6,531,958 7,888,094 5,602,023 1,527,475
Net cash used in operating activities (2,097,822) (3,164,333) (4,456,973) (2,635,533)
Investing activities:        
Purchases of office equipment (47,025) (10,539) (17,728) (4,755)
Net cash used in investing activities (47,025) (10,539) (17,728) (4,755)
Financing activities:        
Proceeds from sale of common stock, net    6,216,762 6,210,537   
Net proceeds from common stock pursuant to the equity line 470,475    528,051   
Proceeds from exercise of warrants and options 28,079 184,286 235,975   
Net cash provided by financing activities 498,554 6,401,048 6,974,563  
Net increase (decrease) in cash and cash equivalents (1,646,293) 3,226,176 2,499,862 (2,640,288)
Cash and cash equivalents at beginning of period 5,856,242 3,356,380 3,356,380 5,996,668
Cash and cash equivalents at end of period 4,209,949 6,582,556 5,856,242 3,356,380
Supplemental disclosure of non cash investing and financing activities:        
Warrants issued in unit offering    4,827,788 4,827,788   
Reclassification of warrant liability to additional paid in capital relating to warrants exercised 1,055,490 201,311 201,311   
Supplemental information:        
Cash paid for state income taxes     $ 3,080 $ 2,730