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Stock Option Plans and Warrants to Purchase Common Stock (Details 3) (Warrant [Member], USD $)
12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Mar. 31, 2013
Mar. 31, 2012
Warrant [Member]
       
Summary of options/warrants activity        
Beginning Balance 2,701,569 2,703,819    
Granted 774,873 4,750    
Number of stock issued from stock option exercises          
Expired (633,104) (7,000)    
Ending Balance 2,843,338 2,701,569    
Beginning Balance, weighted average options/warrants exercise price $ 4.40 $ 4.40 $ 3.13 $ 4.32
Granted, weighted average options/warrants exercise price $ 0.56 $ 3.85    
Exercised, weighted average options/warrants exercise price          
Expired, weighted average warrant exercise price $ 5.40 $ 0.66    
Ending Balance, weighted average options/warrants exercise price $ 3.13 $ 4.40 $ 3.13 $ 4.32