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Consolidated Statements of Cash Flows (USD $)
12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Operating activities:    
Net loss $ (4,163,008) $ (2,378,594)
Adjustments to reconcile net loss to net cash used in operating activities:    
Amortization and depreciation 230,630 226,027
Common stock issued for amended license agreement    400,000
Issuance of common stock to employee 10,000 20,500
Common stock issued in exchange for services 21,000 26,184
Warrants replaced in exchange for renegotiated agreement 429,902   
Stock-based compensation 462,170 715,805
Capitalized patent write-off    88,727
Change in operating assets and liabilities:    
Grants receivable 23,165 (241,686)
Taxes receivable 574,157 (322,293)
Prepaid expenses 55,069 (8,268)
Accounts payable (179,053) (370,620)
Accrued compensation (99,565) (107,520)
Total adjustments 1,527,475 426,856
Net cash used in operating activities (2,635,533) (1,951,738)
Investing activities:    
Acquisition of intangible assets    (151,086)
Purchase of office equipment (4,755) (1,578)
Net cash used in investing activities (4,755) (152,664)
Financing activities:    
Net proceeds from sale of common stock      
Settlement of broker fees associated with 2010 financing    40,743
Proceeds from sale of common stock pursuant to equity line    355,000
Proceeds from exercise of options and warrants    253,613
Net cash provided by financing activities    649,356
Net decrease in cash and cash equivalents (2,640,288) (1,455,046)
Cash and cash equivalents at beginning of period 5,996,668 7,451,714
Cash and cash equivalents at end of period 3,356,380 5,996,668
Supplemental information:    
Cash paid for state income taxes $ 2,730 $ 2,750